Final MN 650 Specialized Pharmacology for the AGACNP Final Exam Latest Update
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Course
MN 650 Specialized Pharmacology for the AGAC
Institution
MN 650 Specialized Pharmacology For The AGAC
Final MN 650 Specialized Pharmacology for the AGACNP Final Exam Latest Update
Common infections in the Geriatrics - ANSWER-MRSA- (uncommon from animals)
Assess body systems function level prior to prescribing ABX therapy - ANSWER-(i.e. renal function).
Antifungals metabolize through the - ANSWER...
Final MN 650
Specialized
Pharmacology for the
AGACNP Final Exam
Latest Update
Common infections in the Geriatrics - ✔✔✔ANSWER-MRSA- (uncommon from
animals)
Assess body systems function level prior to prescribing ABX therapy -
✔✔✔ANSWER-(i.e. renal function).
Antifungals metabolize through the - ✔✔✔ANSWER-Liver
,▪An antibiogram is: - ✔✔✔ANSWER-overall profile of antimicrobial
susceptibility testing results of a specific microorganism to a battery of
antimicrobial drugs
Cultures and sensitivity tell you - ✔✔✔ANSWER-Tells you:
-Identifies bacteria/fungus present
-Sensitivity results based on data
Cultures and sensitivity DONT tell you: - ✔✔✔ANSWER--Infection vs.
colonization vs. contamination
-You would not treat colonization or contamination
-Which ABX to use.
MIC (Minimum inhibitory concentration) - ✔✔✔ANSWER-min. concentration of
an ABX needed to inhibit proliferation & is important for definitive TX.
Cultures and sensitivity reports start with: - ✔✔✔ANSWER-Start w/ beta-lactam
if possible, especially in severe infections (best data supporting their use)
-Exception: atypical infections
▪You are reviewing a report on a urine culture of a 55 year old female with
pyelonephritis. A culture was done which has revealed growth of Ecoli
Susceptibility testing show minimum inhibitory concentration (MIC) score of 1 for
Ciprofloxacin 2 for Levafloxacin 4 for Ceftriaxone and 16 for Nitrofurantoin.
Considering the MIC score the most appropriate antibiotic to prescribe would be
ciprofloxacin. - ✔✔✔ANSWER-Chose lower MIC score
,Fluroquinolones (ex: ciprofloxacin) are most associated with causing: -
✔✔✔ANSWER-pseudomembranous colitis.
S/S of pseudomembranous colitis - ✔✔✔ANSWER-recent ABX use followed by
diarrhea with possible blood
To prevent further development of ABX resistance, it is recommended that
fluoroquinolones be reserved for treatment of: - ✔✔✔ANSWER-CAP with
comorbidities.
If your patient is allergic to sulfonamides, they most likely will have a cross-
sensitivity to: - ✔✔✔ANSWER-loop diuretics, sulfonylureas, & thiazide diuretics.
If you patient cannot reliably take PO ABX, ___ or ___ would be an appropriate
treatment option. - ✔✔✔ANSWER-IM or IV
Prebiotics are recommended to be co-administered with: - ✔✔✔ANSWER-ABX
Rx half-life is longer in: - ✔✔✔ANSWER-older adults (watch for atypical
reactions)
Monitor liver enzymes when on __ tx. - ✔✔✔ANSWER-long term antifungal tx
Patients taking isoniazid for TB may experience peripheral neuropathy. To prevent,
prescribe: - ✔✔✔ANSWER-pyridoxine (vit B6).
, Because microbiological results do not become available for 24 to 72 hours, initial
therapy for infection is often _____ and guided by the clinical presentation. -
✔✔✔ANSWER-empiric
empiric is broad-spectrum & treats: ____
Once C&S is received, a more narrowed focused ABX can be prescribed. -
✔✔✔ANSWER-gram-positive and gram-negative, diverse fungi, or parasites
How soon should newly diagnosed HIV patients should start antiviral treatment? -
✔✔✔ANSWER-as soon as the positive diagnosis is given
Initiation of ARV can prevent complications of AIDS-related diseases, such as: -
✔✔✔ANSWER-PCP pneumonia. (pneumocystis jiroveci pneumonia)
When a Herpes Simplex 2 Dx is suspected ___ is the Rx of choice. -
✔✔✔ANSWER-Acyclovir
You are evaluating a patient in the ER who is complaining of pain to his right leg
that developed yesterday. The pain has become increasingly worse in the last few
hours to the point that the patient's wife called EMS to the house to transport him
to your ER. His wife tells you he has not been acting right over the last few hours
and seems "out of it.". You, the AGACNP suspect an infection and order
labs/cx/start abx. While initiating therapy the patient becomes hypotensive and is
given a fluid bolus. You preform an in-depth exam on this patient and notice
crepitus on the patient's right thigh. You admitted him to your ICU and write orders
to initiate broad spectrum antibiotics for this patient. The best antimicrobial
combination to begin on this patient is _______ - ✔✔✔ANSWER-Doribax (for
nec fasc)
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