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Exam (elaborations)

CSB601 Questions and Correct Answers the Latest Update

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  • CSB601
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  • CSB601

The role of TGA Part of Department of Health that regulates therapeutic goods What classify as therapeutic goods Medicines and blood products, Medical devices, Biologicals Difference between AUST R, AUST L and AUST L(A) AUST R - registered high risk medicines that requires pre-market assess...

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  • November 7, 2024
  • 34
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • CSB601
  • CSB601
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CSB601 Questions and Correct Answers
the Latest Update
The role of TGA


✓ Part of Department of Health that regulates therapeutic goods



What classify as therapeutic goods


✓ Medicines and blood products, Medical devices, Biologicals



Difference between AUST R, AUST L and AUST L(A)


✓ AUST R - registered high risk medicines that requires pre-market assessment
✓ AUST L - contemporary medicines that hasn't been been assessed for efficacy
✓ AUST LA - listed medicines that had to provide proof of



Principles of QUM


✓ Safety
✓ Efficacy
✓ Appropriate
✓ Judicious



What are generic brands of medications


✓ Medication that has been proved to have the bioavailability of the branded drugs



Problems with Medication



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✓ Adverse medicine events
✓ Adverse medicine reactions
✓ Inappropriate selection
✓ Dosing
✓ w/o indication
✓ Interactions
✓ Untreated indications



Pharmacokinetics


✓ what the body does to the drug (ADME)



What is pharmacodynamics?


✓ What the drug does to the body
✓ - intended effect
✓ - side effect



What does ADME stand for in pharmacokinetics?


✓ Absorption: oral, sublingual, blood vessel, GIT
✓ Distribution: Blood vessel, Lymphatic vessel, CNS fluid
✓ Metabolism: Liver, Kidney, Lung
✓ Excretion: Kidney



Bioavailability


✓ A measure (%) of the extent of drug absorption from site of administration and site
of action for a given drug and route.



What is half-life of a medication



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✓ The time it takes for plasma concentration of a drug to decrease by half, which
determines the dosing frequency



Interactions between Digoxin and potassium-losing diuretics


✓ Increase arrhythmias, since potassium-losing diuretics can result in potassium
depletion



What medication interacts with NSAIDs


✓ - ACE-inhibitors (Decrease effects)
✓ - Diuretics (Decrease effects)
✓ - Sulfonylureas (Increase hypoglycemic effect)
✓ - Lithium (toxicity)
✓ - Digoxin



Key parameters of Pharmacokinetic


✓ - Half Life
✓ - Volume of Distribution
✓ - Bioavailability
✓ - Clearance



Classes of Antidepressants


✓ SSRIs, SNRIs, TCAs, MAOIs



What class of drugs is Phenelzine and Tranylcypromine


✓ MAOIs



Drug class: Fluvoxamine, Sertraline

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✓ SSRIs



Interaction: SSRIs/SNRIs with NSAIDs


✓ Increase risk of bleeding



Interaction: SSRIs/SNRIs with Tramadol


✓ Increase risk of Serotonin Syndrome



What are precautions of lithium use in women


✓ - Increase the risk of congenital heart defects in pregnancy, neonatal neurotoxicity
and hypothyroidism
✓ - Lithium concentration in pregnancy



What the triple whammy of the medications


✓ ACE-inhibitors
✓ Diuretics
✓ NSAIDs
✓ - Causing increased risk in AKI



Interaction between diuretics and ACE inhibitors/ARBs


✓ postural hypotension



What's the symptoms of Serotonin Toxicity




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