Exam (elaborations)
MN553 Unit 5
- Course
- Institution
Exam of 13 pages for the course MN553 Unit 5 at MN553 Unit 5 (MN553 Unit 5)
[Show more]
Content preview
MN553 Unit 5Examples of biguonides - -Metformin
Fortamet
Glucophage
- Biguanides MOA - -Activates AMP-kinase to hepatic glucose production
- Buganides advantages - -Weight neutral
No hypoglycemia
Modest decline in LDL
- SE of biguanides - -Nausea
Diarrhea
Cramps
Rarely harmful buildup of lactic acid (lactic acidosis)
- Examples of sulfonylureas - -Glipizide (Gluctrol)
Clmepride (Amaryl)
Glyburide
Glipazide
- Sulfonylureas MOA - -Closes KATP channels on beta cell plasma
membranes
Insulin secretion
- Examples of rapid acting insulin - -Lispro (Humalog)
Aspart (Novolog)
Glulisine (Apidra)
- Rapid acting insulin onset - -About 5 minutes
, - Rapid acting insulin peak - -About 1 hour
- Rapid acting insulin duration - -4-5 hours
- Examples of short acting insulin - -"Regular" (Humalin)
- When is Humalin sometimes used - -Around meal time
- When ins Humalin taken - -About 30-45 minutes before eating
- When does Humalin peak - -3-4 hours
- Humalin duration - -4-10 hours
- Characteristics of inermediate acting insulin - -Normal pressure
hydrocephalus mixed with protamine
Delaying absorption
Looks cloudy and has to be mixed before it is injected
- Intermediate insulin onset - -30 minutes to 1 hour
- Intermediate insulin peak - -4-10 hours
- Intermediate insulin duration - -12-24 hours
- Examples of long acting insulin - -Glargine (Lantus)
Detemir (Levemir)
Degludec (Tresiba)
- Long acting insulin onset - -2-4 hours
- Long acting insulin duration - -24 hours with little to no peak
- Sulfonylureas advantages - -Microvascular risk
- Sulfonylureas SE - -Hypoglycemia
Weight gain
Nausea
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Nursephil2023. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
72042 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now