OCN Study Guide-derived directly from the Core Curriculum for
Oncology Nursing, The ONS Chemotherapy/Biotherapy Text, and
Mosby's Oncology Nursing Advisor. 100% Solved | Top graded A+
Abnormalities of what electrolyte and what mineral interfere with cardiac function?
- ✔✔Potassium and Calcium
What med can be used to protect heart against effects of doxorubicin - ✔✔Dexrazoxane
Spiral CT - ✔✔Diagnostic test for pulmonary emboli
D-DImer test - ✔✔used to diagnose or rule out conditions that cause
hypercoagulability (inappropriate clotting)
DIC - ✔✔Accelerated activation of the coagulation cascade. Clots form in random places
leaving the body open to bleeding without protection
Platelet count, Fibrinogen level, D Dimer, FDP Titer - ✔✔Tests to diagnose DIC
How to treat DIC - ✔✔Treat underlying cause
What does FFP do? - ✔✔Contains all of the clotting factors except platelets. Used to
supplement red blood cells when whole blood is not available or to correct a bleeding problem
of unknown cause. It is also used to correct DIC.
,Most common cancer associated with DIC? - ✔✔Leukemia, specifically APL
Signs/Symptoms of DIC - ✔✔bleeding from 3 unrelated sites
hypoxia
SOB
fever
mottled extremities
Causes of DIC - ✔✔Delivery (of baby)
Infection
Cancer
How does Heparin help DIC? - ✔✔Interferes with thrombin production. Maintain PTT at 1-
2 times the normal level (18-28 seconds)
S/S of septic shock - ✔✔Fever
Tachycardia
Hypotension
Most common cause of sepsis - ✔✔Gram (-) bacteria
DIC - ✔✔Accelerated activation of the coagulation cascade. Clots form in random places
leaving the body open to bleeding without protection
Platelet count, Fibrinogen level, D Dimer, FDP Titer - ✔✔Tests to diagnose DIC
How to treat DIC - ✔✔Treat underlying cause
,What does FFP do? - ✔✔Contains all of the clotting factors except platelets. Used to
supplement red blood cells when whole blood is not available or to correct a bleeding problem
of unknown cause. It is also used to correct DIC.
Most common cancer associated with DIC? - ✔✔Leukemia, specifically APL
Signs/Symptoms of DIC - ✔✔bleeding from 3 unrelated sites
hypoxia
SOB
fever
mottled extremities
Causes of DIC - ✔✔Delivery (of baby)
Infection
Cancer
How does Heparin help DIC? - ✔✔Interferes with thrombin production. Maintain PTT at 1-
2 times the normal level (18-28 seconds)
S/S of septic shock - ✔✔Fever
Tachycardia
Hypotension
Most common cause of sepsis - ✔✔Gram (-) bacteria
Granulocytopenia - ✔✔failure of the bone marrow to make enough
white blood cells (neutrophils)
, Highest risk factor for sepsis - ✔✔Prolonged granulocytopenia (less than 500/mm3)
What cancer commonly produces TLS? - ✔✔High grade lymphoma
Define Tumor Lysis Syndrome (TLS) - ✔✔metabolic imbalance that occurs with rapid tumor kill
Lab results indicating DIC - ✔✔Increased D Dimer
Increased FDP
Phos
Uric Acid
Calcium
LDH
Renal function (BUN, Creatinine)
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