NR 566 MIDTERM EXAM TEST BANK
ADVANCED PHARMACOLOGY
1. Which of the following drugs is a nonselective beta blocker that is commonly used
to treat hypertension and anxiety?
A) Atenolol
B) Propanolol
C) Metoprolol
D) Carvedilol
Answer: B) Propanolol
2. Which of the following mechanisms is responsible for the pharmacological effect
of digoxin?
A) Inhibition of the Na+/K+ ATPase pump
B) Inhibition of the L-type calcium channel
C) Blockade of alpha-adrenergic receptors
D) Inhibition of the serotonin reuptake transporter
Answer: A) Inhibition of the Na+/K+ ATPase pump
3. What is the primary side effect of opioid analgesics that requires careful
monitoring in patients receiving these drugs long-term?
A) Hyperkalemia
B) Respiratory depression
C) Tinnitus
D) Bradycardia
,Answer: B) Respiratory depression
4. Which of the following antibiotics is most likely to cause a disulfiram-like reaction
if taken with alcohol?
A) Penicillin
B) Ciprofloxacin
C) Metronidazole
D) Amoxicillin
Answer: C) Metronidazole
5. Which of the following classes of drugs is primarily used to manage type 2
diabetes by increasing insulin sensitivity in peripheral tissues?
A) Biguanides
B) Sulfonylureas
C) Thiazolidinediones
D) DPP-4 inhibitors
Answer: C) Thiazolidinediones6. Which of the following drugs is an irreversible
inhibitor of cyclooxygenase (COX-1 and COX-2) and is commonly used for its anti-
inflammatory effects?
A) Acetaminophen
B) Ibuprofen
C) Aspirin
D) Celecoxib
Answer: C) Aspirin
,7. Which of the following is the most common adverse effect associated with the use
of statins (HMG-CoA reductase inhibitors)?
A) Liver toxicity
B) Rhabdomyolysis
C) Hypertension
D) Tinnitus
Answer: B) Rhabdomyolysis
8. Which of the following is the primary mechanism of action of the angiotensin-
converting enzyme (ACE) inhibitors?
A) Blockade of beta-adrenergic receptors
B) Inhibition of aldosterone secretion
C) Inhibition of angiotensin II synthesis
D) Blockade of calcium channels
Answer: C) Inhibition of angiotensin II synthesis
9. Which of the following medications is commonly prescribed for the management
of chronic obstructive pulmonary disease (COPD) and acts as a long-acting
muscarinic antagonist?
A) Salmeterol
B) Ipratropium
C) Tiotropium
D) Montelukast
Answer: C) Tiotropium
, 10. A patient is started on warfarin therapy. Which of the following laboratory tests
is primarily used to monitor the therapeutic effect of warfarin?
A) Prothrombin time (PT)
B) Partial thromboplastin time (aPTT)
C) International normalized ratio (INR)
D) Thrombin time (TT)
Answer: C) International normalized ratio (INR)
11. Which of the following is a significant adverse effect of hydrochlorothiazide, a
thiazide diuretic?
A) Hyperkalemia
B) Hypoglycemia
C) Hypokalemia
D) Hypercalcemia
Answer: C) Hypokalemia
12. Which of the following is a contraindication for the use of nonsteroidal anti-
inflammatory drugs (NSAIDs)?
A) Hypotension
B) Asthma
C) Gastrointestinal ulcers
D) Hyperlipidemia
Answer: C) Gastrointestinal ulcers
13. Which of the following is the mechanism of action of selective serotonin
reuptake inhibitors (SSRIs)?
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