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(4) thinners and pumpers exam with complete solutions latest update
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(4) thinners and pumpers exam with completesolutions latest update
angina - ANSWER occurs when oxygen demand is greater than oxygen supply
cholesterol lowering agents and blood thinners - ANSWER drug classes used in
treatment of angina to prevent myocardial infarction
platelet plug formation - ANSWER what is primary hemostasis
local vasoconstriction, platelet adhesion, platelet activation, aggregation and fibrinogen
bridge formation - ANSWER what is included in platelet plug formation
collagen and von willebrand factor - ANSWER what is involved in platelet adhesion
thrombin, thromboxane a2, and adp - ANS what is involved in platelet activation
iib and iiia - ANS in the formation of a platelet plug, a fibrinogen bridge forms between
glycoproteins:
coagulation - ANS what is secondary hemostasis
secondary - ANS extrinsic, intrinsic, and common pathways are involved in
________________ hemostasis
xa - ANS activated factor X
thrombin - ANS activated prothrombin
,fibrin - ANS activated fibrinogen
Extrinsic, intrinsic and common pathways are activated, Factor X is activated into Xa, Xa
activated prothrombin into thrombin, Thrombin activates Fibrinogen into Fibrin -
ANSWER What is the process of secondary hemostasis
TPA - ANSWER Activates plasminogen to Plasmin
Cyclooxygenase inhibitors (COX inhibitors), P2Y12 ADP receptor antagonists, PAR-1
antagonists, Platelet glycoprotein IIb/IIIa inhibitors - ANSWER What are the classes of
antiplatelets
COX inhibitor - ANSWER Aspirin is classified as a :
aspirin - ANSWER if a patient comes into the emergency room with suspected mi, they
will be administered what medication
myocardial infarction, stroke, angina - ANSWER therapeutic uses of aspirin
aspirin - ANSWER works by irreversibly inhibiting cyclooxygenase, blocking platelet
aggregation
baby - ANSWER patients at risk for mi or stroke will be on a __________ aspirin
low - ANSWER _______ dose aspirin is important for prevention of clots is important to
prevent inhibition of prostacyclin
clopidogrel and -grels - ANSWER what are the ADP antagonists
prevent platelet aggregation - ANSWER ADP antagonists are used to:
ADP antagonists - ANSWER work by irreversibly blocking platelet aggregation by
blocking the ADP receptor, P2Y12
bleeding, thrombotic thrombocytopenic purpura - ANSWER what are adverse effects of
clopidogrel
, 5 days - ANSWER patients on ADP antagonists should stop ____________ prior to elective
surgery (not related to the heart)
false - ANSWER t/f patients who are bleeding unexpectedly with ADP antagonists should
stop the medication immediately
thrombocytopenia, hemolytic anemia, neurologic symptoms, petechiae, renal
dysfunction, fever - ANSWER what is s/s of thrombotic thrombocytopenic purpura
true - ANSWER t/f if thrombotic thrombocytopenic purpura this requires urgent
treatment
plasmaphresis - ANSWER used to treat thrombotic thrombocytopenic purpura
vorapaxar - ANSWER what is the PAR-1 antagonist
eptifibatide and tirofiban - ANSWER what are the GPIIa/IIIb inhibitors
short term to prevent ischemia, slow rapid re-occlusion after pci placement - ANSWER
what are the therapeutic uses of gpiia/iiib inhibitors
GPIIa/IIIb inhibitors - ANSWER work by blocking platelet aggregation by blocking
GPIIa/GPIIIb
bleeding and hypotension - ANSWER adverse effects of GPIIa/IIIb inhibitors
false ANSWER t/f The headless horseman is taking clopidogrel following the placement
of a coronary artery stent due to one-too-many scares. Mr. Horseman calls the Sleepy
Hollow doctors office to inform them he is vomiting and it looks like coffee grounds. The
nurse screens his call and instructs Mr. Horseman to immediately stop taking the
medication and wait until he speaks with his doctor before taking the next dose.
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