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NUR 641 E FINAL EXAM STUDY GUIDE GRAND CANYON UNIVERSITY QUESTIONS AND ANSWERS 2024
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NUR 641 E FINAL EXAM STUDY GUIDE GRAND CANYON UNIVERSITY QUESTIONS AND ANSWERS 2024
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NUR 641 E FINAL EXAM STUDY GUIDE GRANDCANYON UNIVERSITY
Cause and result of cross resistance seen with penicillin and cephalosporins -
ANSWERS-1. medications contain beta lactam ring that the enzyme beta
lactamase from an organism can attack and destroy
2. render antibiotic ineffective not the organism
Antibiograms - ANSWERS-charts of local antimicrobial resistance patterns
developed by local laboratories
Clostridum Difficile (C-Diff) - ANSWERS-1. organism producing a toxin that causes
antibiotic associated pseudomembranous colitis (AAPMC)
2. diarrhea occurs often with clindamycin use
Glucose-6-phosphate dehydrogenase deficiency (G6PD) patients - ANSWERS-
increased side effects when given along with sulfonamides
avoid use of sulfa drugs
Isoniazid (INH) - ANSWERS-1. used to treat TB
2.given with vitamin b6 to reduce peripheral neuropathy side effect
Tetracycline - ANSWERS-1. stunt growth in children and should not be used
,2. doxcycline and minocycline are safe for teenagers
3. short term use in pregnant women require second contraceptive like condom
until she gets her period again
Heart patients undergoing dental procedures - ANSWERS-prophylactics antibiotics
are not required under current guidelines
medication used for right sided endocarditis due to staph - ANSWERS-Daptomycin
pyrogenic bacteria - ANSWERS-1.bacteria that produce endotoxins
2. stimulate inflammatory response that results in fever
Invasion period of infection - ANSWERS-immune and inflammatory responses are
initiated
vertical transmission - ANSWERS-from parent to child transmission across the
placental barrier
Horizontal transmission - ANSWERS-transmission of organism from one person to
another typically through direct contact
Passive acquired immunity - ANSWERS-passages if immunoglobulin across the
placental barrier
,Combination of Beta lactam and beta lactamase inhibitors - ANSWERS-1. increase
the antimicrobial spectrum of activity of beta lactam antibiotic
2. Augmentin combination of Amoxicillin and clavulanic acid
3.Zosyn: piperacillin and tazobactam used for pseudomonas
4. Unasyn: combination of ampicillin and sulbactam
5. ceftriaxone and sulbactam
Fluroquinolones - ANSWERS-1. pneumonia and exacerbated chronic bronchitis
2. decrease potential for development of further resistance
3. not active vs MRSA
4. interact with minerals in foods and vitamins
5. space dosing away from meals containing iron, calcium and magnesium
6. interact with dairy products and foods containing calcium and magnesium
7. increase warfarin effect
8. decrease caffeine clearance
9. require monitoring for joint pain
10. tendon rupture are associated with use
Cotrimoxazole (trimethoprim + sulfamethoxazole) AKA Bactrim - ANSWERS-1.
used to treat UTI
2. work great for people not previously taking antibiotics
, Urinary Tract Infections - ANSWERS-1. elderly patient may have stomach pain and
confusion
2. E coli is most common bacteria it is gram negative
Amphotericin B - ANSWERS-1. requires close renal function monitoring
2. possible nephrotoxicity
3. ototoxicity monitor hearing
C-diff medication treatment - ANSWERS-Metronidazole and oral vancomycin
Metrodinazole (Flagyl) education - ANSWERS-avoid alcohol during medication
therapy and two days post last dose
Fluconazole (Diflucan) - ANSWERS-Antifungal
Candida albicans
drug interactions -may cause hepatic enzyme inhibition
Ketoconazole (Nizoral) hepatic enzyme monitoring - ANSWERS-ALT
AST
Alkaline Phosphate
Bilirubin
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