Diagnosing Acute Lymphoblastic Leukemia Exam Bank Solution Manual Latest Update 2024 (Already Passed)
Hematopoiesis - Answers Production of all blood cells in the red bone marrow.
Pluripotent Stem Cell - Answers Stem cell generating all blood cells.
Lymphoid Stem Cell - Answers Stem cell differe...
Granulocyte - Answers Differentiated myeloblast, includes neutrophils, eosinophils, basophils.
B Lymphoblast - Answers Differentiated lymphoblast on the B cell pathway.
T Lymphoblast - Answers Differentiated lymphoblast on the T cell pathway.
T Cells - Answers Mature from T lymphoblasts, further specialize in the thymus.
B Cells - Answers Mature from B lymphoblasts, found in lymph nodes.
Acute Lymphoblastic Leukemia - Answers Problem where lymphoblasts fail to fully differentiate into T
and B cells.
DNA Mutations - Answers May occur due to chemo radiation, leading to uncontrolled cell replication.
Genetic Etiologies - Answers Possible predisposition, including Down syndrome (Trisomy 21).
Fusion Gene - Answers Result of swapping genetic material between chromosomes, leading to immortal
cells
Translocation - Answers Genetic abnormality where genetic material is exchanged between non-
homologous chromosomes
15;17 Translocation - Answers Specific translocation associated with APL, leading to the formation of a
Fusion Gene
12;21 Translocation - Answers Common in children with ALL, involves swapping genetic material
between chromosomes 12 and 21
9;22 Translocation - Answers Associated with adults in ALL, involves exchanging genetic material
between chromosomes 9 and 22
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