Management of BMI >/=35 + cormorbidity - Answer Bariatric surgery
Management of BMI >/=40 - Answer Bariatric surgery
Co-morbidities - Answer T2DM
HTN
OSA and other respiratory disorders
NAFLD
OA
lipid abnormalities
gastrointestinal disorders
heart disease
Medication assessment - Answer Every month x3 months, then every 3 months
Effective weight loss % - Answer >/=5% in 3 months
Avoid these wt loss meds with HTN/HD - Answer Sympathomimetics (phentermine/diethylproprion)
,Avoid these wt loss medications with CVD - Answer Sypathomimetics
T2DM treatment + medications to support weight loss - Answer GLP-1 analog (mitigates associated
weight gain due to insulin) or SGLT-2 inhibitors + metformin. If using insulin, recommend basal instead of
combo
Drugs that induce weight gain - Answer Tricyclic antidepressants (Amitriptyline)
oral contraceptives (Ortho Tri-Cyclen, Yaz)
antipsychotics (Risperidone)
anticonvulsants
glucocorticoids (cortisol)
sulfonyureas- ( Glimepiride, Glipizide)
glitazones (Actos)
B-blockers (Propranolol, Metoprolol, Atenolol)
Hormonal signals for appetite - Answer CCK- duodenum
K cells- duodenum and jejunum: gatric inhibitory polypeptide
PYY- ileum and colon
GLP-1 -ileum
Pancreas- Insulin
Adipose tissue: Leptin
Liver- glucagon
GLP-1 - Answer Secreted in response to glucose and promotes insulin release from pancreas and
satiety
Ghrelin - Answer produced in the stomach, orexigenic
, Leptin - Answer proportional to fat mass, anorexigenic
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