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VTE TREATMENT: DOACS EXAM 2024/2025 $16.49   Add to cart

Exam (elaborations)

VTE TREATMENT: DOACS EXAM 2024/2025

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VTE TREATMENT: DOACS EXAM 2024/2025

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  • November 11, 2024
  • 5
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • VTE TREATMENT: DOACS
  • VTE TREATMENT: DOACS
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YANCHY
VTE TREATMENT: DOACS EXAM 2024/2025


Dabigatran (Pradaxa) pros - Precise Answer ✔✔Reversible
Preferred agent on Kaiser formulary


Dabigatran (Pradaxa) cons - Precise Answer ✔✔Higher risk of GI
bleeding in patients >75
PGP DDIs
Requires 5 days of parenteral therapy


Dabigatran (Pradaxa) dose - Precise Answer ✔✔150 mg BID
Requires 5 days of parenteral therapy


Dabigatran (Pradaxa) contraindications - Precise Answer ✔✔CrCl < 30
mL/min
ESRD/HD


Dabigatran (Pradaxa) DDIs - Precise Answer ✔✔P-gp inducers or
inhibitors


Strong CYP3A4 inducers and inhibitors

, Dabigatran (Pradaxa) key points - Precise Answer ✔✔Reversible with
Idarucizumab


Apixaban pros - Precise Answer ✔✔Does not require parenteral therapy
first


Immediate anticoagulation - outpatient


Reversible and fewer DDIs


Can be given via G-tube or J-tube


Can be used with CrCl < 30 mL/min


Apixaban cons - Precise Answer ✔✔More expensive
Cannot monitor
Reversal agent is very expensive


Apixaban dose - Precise Answer ✔✔10 mg BID for 7 days
5 mg BID


Can dose reduce by 50% with strong CYP3A4 and P-gp inhibitors

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