What drug-drug interaction occurs with tetracyclines and divalent/trivalent
cations - ANSWERS-Coadministration of tetracyclines and antacids, iron salts,
sevelamer, or Mg containing laxatives decreases the antibiotic activity and these
medications should be given at least 2 hours apart.
Contraindications for use of Tetracyclines - ANSWERS-Renal failure (except
Doxycycline/Vibramycin)
No children under 8
Pregnancy Cat X
What are some adverse effects of Vancomycin - ANSWERS-ototoxicity,
nephrotoxicity, red man syndrome
2nd line treatment of MRSA - ANSWERS-gentamycin
What are some adverse effects of aminoglycosides? - ANSWERS-ototoxicity and
nephrotoxicity
Contraindications to use of aminoglycosides - ANSWERS-patients with Myasthenia
Gravis due to neuromuscular blockade
,Considerations when using Linezolid - ANSWERS-Can interact with MAOIs, SSRIs,
and serotonin agonists
Follow low tyramine diet
Do not use any OTC cold meds with adrenergic drugs in them
do not use longer than 28 days due to increase risk of peripheral and optic
neuropathy.
What are some adverse effects of Nitrofurantoin - ANSWERS-Brown urine
Hepatitis
Hemolytic anemia
Acute and Chronic pulmonary reactions
peripheral neuropathy
What antibiotics are bactericidal - ANSWERS-Penicillins
Cephalosporins
Fluoroquinolone
Macrolides (to some organisms in large doses)
Nitrofurantoin
Oxazolidinone (for most strains of strep)
Vancomycin
Aminoglycosides
Metronidazole
, What antibiotics are bacteriostatic - ANSWERS-sulfonamides
tetracyclines
clindamycin
macrolides
Oxazolidinone (for MRSA)
Which antifungal drugs can be used for systemic illnesses - ANSWERS-
Ketoconazole
Fluconazole
Itraconazole
Voriconazole
Caspofungin
Terbinafine
Which antifungal drugs are only used for superficial infections - ANSWERS-
Nystatin
Clotrimazole
Miconazole
What is the drug of choice for vaginal, esophageal, urinary and oropharyngeal
candidiasis - ANSWERS-Fluconazole
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