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Septic Shock Management Exam Questions Answered Correctly (Graded A+)

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Septic Shock Management Exam Questions Answered Correctly (Graded A+) what is the definition of shock - Answers - hypotension, characterized by SBP <90, AMP <70, or decreased of >40 from based line with perfusion abnormalities despite adequate fluid resuscitation - cellular dysoxia: d...

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  • November 12, 2024
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Septic Shock Management Exam Questions Answered Correctly (Graded A+)



what is the definition of shock - Answers - hypotension, characterized by SBP <90, AMP <70, or
decreased of >40 from based line with perfusion abnormalities despite adequate fluid resuscitation

- cellular dysoxia: diminished blood circulation, inadequate blood flow to the tissues, results in anaerobic
metabolism

- hypovolemic shock, cardiogenic shock, obstructive shock [pericardial tamponade, PE], distributive
[septic, anaphylactic, neurogenic]

what is the clinical presentation of shock - Answers - s/sx may initially be subtle

- organ dysfunction

- serum lactate >2mMol/L

what is the definition of Systemic Inflammatory Response Syndrome (SIRS) - Answers generalized
inflammatory response triggered by an infectious or non-infectious event; 2 of the 4 criteria must be
present:

- HR >90

- RR >20 or PaCO2 <32

- temp >38C or <36C

- WBC >12 or <4 or ≥ 10% leukocytes

what is the initial therapeutic management for shock - Answers - establish vascular access: venous
access, central venous catheter

- monitoring devices: arterial catheter, EKG monitoring, pulse oximetry

- provide hemodynamic support: fluid challenge, vasopressors, invasive hemodynamic monitoring

- correct hypotension first, decrease HR, correct hypoperfusion abnormalities, initiate vasopressor
therapy if unable to achieve hemodynamic goals

what are the *goals of resuscitation* from a shock - Answers - *MAP ≥65mmHg*

- HR <100 BPM

- CVP 8 - 12mmHg

- PCWP 12 - 15 mmHg

, - *lactate clearance <2mM/L or concentration >2mM/L*

- SVO2 / SCVO2 >65% /70%

- UO >0.5mL/kg/hr

how do you calculate MAP - Answers [ (2 x diastolic) + systolic ] divided by 3

what is SOFA score - Answers sequential organ failure assessment; a change in 2 indicates worsening
sepsis

- respiratory: PaO2

- neurologic: GCS

- cardiovascular: MAP

- liver: bilirubin

- coagulation: platelet count

- renal: creatinine

what is qSOFA - Answers quick SOFA; not used in the ICU; presence of 2 or more indicates the patient
will likely have a poor outcome

- hypotension (systolic BP 100 or below)

- altered mental status

- tachypnea (RR >22)

how do you assess severe sepsis - Answers - hemodynamics: BP and HR

- O2 delivery: PaO2, HGB

- O2 consumption: ABG, lactate

- tissue perfusion: UO, creatinine, bilirubin, cognition

- DIC: INR, thromcocytopenia

what is early, goal-directed therapy (EGDT) and what do you have to know about it - Answers -
protocolized, quantitative resuscitation of patients with sepsis-induced tissue hypoperfusion

- EGDT in the 1st 6hrs after presentation to the ED with severe sepsis and septic shock was associated
with 16% absolute risk reduction in hospital mortality

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