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NUR 242 Exam One with verified answers

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  • NUR 242

NUR 242 Exam One with verified answers

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  • November 14, 2024
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  • 2024/2025
  • Exam (elaborations)
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  • NUR 242
  • NUR 242
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NUR 242 Exam One with verified
answers


What is pharmacology? - ** VERIFIED ANSWERS **✔✔study of drugs that alter functions of living
organisms



what is pharmacokinetics? - ** VERIFIED ANSWERS **✔✔the study of how the drugs move within
the body to reach sites of action, metabolism, and excretion



What is absorption? - ** VERIFIED ANSWERS **✔✔the process that occurs from the time the drug
enters the bloodstream. Onset of drug action is determined by rate.



What factors affect rate and extent of drug absorption? SATA - ** VERIFIED ANSWERS
**✔✔dosage, form, route

admin site blood flow, GI function

presence of food, other drugs



What is distribution? - ** VERIFIED ANSWERS **✔✔transport of drugs in the body



What carries drugs and where to? - ** VERIFIED ANSWERS **✔✔blood and tissue fluids to action
sites, metabolism sites, excretion sites



What affects distribution? - ** VERIFIED ANSWERS **✔✔protein binding: drugs bind to act as
carriers

blood-brain barrier: extremely small to cross

pregnancy - placenta

lactation - many drugs enter the breast milk

, what is metabolism? - ** VERIFIED ANSWERS **✔✔the way the drugs are inactivated by the body
(cytochrome P-450 enzyme pathway)



what are drugs changed to when metabolized? - ** VERIFIED ANSWERS **✔✔inactive metabolites

active metabolites

pro drugs - drugs that are inactive until metabolized



where are drug metabolizing enzymes located - ** VERIFIED ANSWERS **✔✔kidney, liver, RBCs,
plasma, lungs, GI mucosa



What are factors that affect metabolism? - ** VERIFIED ANSWERS **✔✔enzyme induction -
chronic administration promotes the liver to produce larger amounts of the enzyme and accelerates
metabolism

enzyme inhibition that occurs when two drugs are being given at the same time that utilize the same
enzyme



what is excretin - ** VERIFIED ANSWERS **✔✔elimination from the body



what is the margin of safety for a drug? - ** VERIFIED ANSWERS **✔✔therapeutic index of the
drug



what is required for excretion? - ** VERIFIED ANSWERS **✔✔adequate function of the circulatory
system, kidneys bowel, lungs, and skin



what is polypharmacy? - ** VERIFIED ANSWERS **✔✔taking multiple drugs; puts individuals at
risk for drug interactions



what does it make someone more susceptible to if they're 85 with kidney problems? - ** VERIFIED
ANSWERS **✔✔drug toxicity



what is a drugs "half life" - ** VERIFIED ANSWERS **✔✔the time it takes fo half of the drug to be
eliminated from the body

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