ASCP BOARD OF CERTIFICATION MLT
EXAM LATEST ACTUAL EXAM 2025
QUESTIONS AND DETAILED CORRECT
ANSWERS | ALREADY GRADED A+
A newborn presents with neonatal alloimmune
thrombocytopenia. What is the most likely cause of this
condition? Correct Answer Maternal antibodies to neonatal
platelet antigens
A lipid panel consists of which of the following tests?
Correct Answer Cholesterol, Lipoprotein, HDL,
Triglycerides
How would you describe the arrangement of RBCs on this
slide?
Correct Answer True rouleaux
The cells in this image are from a bone marrow smear.
Identify the cells present in this image:
,Correct Answer Osteoblast
A test that can be used as a confirmatory test for
urobilinogen is: Correct Answer Watson-Schwartz Test
The pI of a protein is 9.2. This protein is placed in an
electrical field where a buffer sets the pH at 10.0. Select
the correct statement regarding the electrophoretic
migration of this protein. Correct Answer This protein will
have a net negative charge and will migrate toward the
anode, the positively charged electrode
A manual white blood cell count was performed by the
hematology technologist. The cell counts for both sides
were 99 and 164, respectively. All nine large squares were
counted on each side. The dilution for this kit was pre-
measured at 1:100. What should the technologist report as
the white cell count? Correct Answer Cannot report
When comparing the white cell counts from one side
of the hemacytometer to the other, there is not good
duplication. Cell counts from opposite sides of the
,hemacytometer (within the same patient sample) that
are greater than 10% of one another are considered
discrepant and should not be used to calculate
reportable results. This particular count should not be
used to report patient results.
The RBC inclusions shown in the photograph represent
which of the following?
Correct Answer Howell-Jolly bodies
Howell-Jolly bodies are usually single, round, and
tend to be positioned at the periphery of the red blood
cell. These inclusions are rarely found on a routine
peripheral blood smear, as they are usually removed
by a functioning spleen. Howell-Jolly bodies appear in
megaloblastic anemias and after splenectomy.
Which of the following tests would be employed in order to
detect neural tube defects? Correct Answer Alpha
fetoprotein
, Alpha-fetoprotein is a protein measured in pregnant
women, using maternal blood or amniotic fluid, as a
screening test for a subset developmental
abnormalities: it is principally increased in open
neural tube defects and decreased in Down syndrome.
A patient has the following serum results:
Na = 130 mEq/LK = 4.9 mEq/LCl = 107 mEq/LGlucose =
300 mg/dLBUN = 18 mg/dLCreatinine = 1.1 mg/dL
Which osmolality result is consistent with these results?.
Correct Answer 281 mosmol/kg
Osmolality = 2 x Na + [Glucose (mg/dL) / 20] + [BUN
(mg/dL)/ 3]
A liquid ion-exchange membrane electrode using the
antibiotic valinomycin is MOST selective for: Correct
Answer Potassium
The valinomycin membrane electrode is most
selective for potassium as opposed to sodium,
glucose, or chloride which utilize different membranes
for their respective electrodes. Valinomycin, which is
neutral in charge, has been incorporated into organic
liquid membranes resulting in a sensor with a very
high selectivity for potassium.
What should safety management start with in order to
ensure clarity and consistency? Correct Answer A written
safety policy
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