Exam (elaborations)
APHON PRINCIPLES OF BIOTHERAPY EXAM
- Course
- Institution
APHON PRINCIPLES OF BIOTHERAPY EXAM...
[Show more]
Content preview
APHON PRINCIPLES OF BIOTHERAPYEXAM
Biotherapy: ANSWER mode of treatment: substances that mimic the body's
natural defensive and monitoring mechanisms. can direct anticancer activity,
enhance, modify, and repair the host's immunological ANSWER, among other
biological actions. usually hypersensitivity rx side effects
Immune surveillance: ANSWER tumour cells display aberrant tumour antigens
on their surface that the immune system can identify and eliminate.
Natural killer cells are ANSWER lymphocytes that identify and eliminate
cancerous cells.
ANSWER's cytotoxic T lymphocytes identify antigens linked to tumours and
eliminate cells.
Interferons are made with recombinant DNA and have several moas.
protein that inhibits viral replication to protect other cells from viral infections.
Glycoproteins have strong immunomodulatory, antiviral, and antiproliferative
properties.
Cytokines are ANSWER products produced by immune cells that boost immune
ANSWER and cell cytotoxic action.
hairy cell leukemia, melanoma, chronic myeloid leukemia, follicular lymphoma,
multiple myeloma, and cutaneous t-cell lymphoma. alpha-interferon-ANSWER
leukocyte-derived
ANSWER fibroblast-derived beta-interferon. tx MS
ANSWER t-lymphocyte-derived gamma-interferon. Chronic
Granulomatomatus Disease in Texas
, T-helper cells produce interleukin-2-ANSWER, which promotes the
development of cytotoxic T-cells, lymphokines, and cytokines as well as the
growth and maturation of t-cell subsets.
function as chemical messengers between WBCs (stimulating the immune
system)
Retinoids are ANSWER immunomodulators that promote cancer cell
differentiation and inhibit their growth.
ANSWER: all-trans retinoic acid (atra) tx: aml, aml m3 subtype, apl promote
promyelocytic blast maturation and coagulopathy resolution quickly in relation
to tx.
ANSWER retinoid tx neuroblastoma is treated with isotretinoin (accutane).
possess unknown moa antitumor activity. TERATOGENIC. Both male and
female patients need to sign up for iPledge (fetal exposure). can impact eyesight
and hearing as well.
ANSWER proteins, or antibodies, are made by b-lymphocytes. component of
the adaptive system's humoral immunity. consists of immunoglobulins (igG,
igA, igM, igE, and igD).
ANSWER microscopic-derived Human antimouse antibodies are produced by
MoAbs, increasing the likelihood of hypersensitivity. Rx ends in -momab.
ANSWER monoclonal antibodies are highly specific. targeted at a single
antigenic determinant on the cell surface that results in mild toxicity, antibody-
dependent cellular toxicity, direct cell death, and antigen/target cell elimination
-ximab-ANSWER moab combination of mouse and human antibodies
-zumab - ANSWER moab humanized, human antibody fused with a tiny portion
of mouse antibodies
ANSWER completely humanized moabs -umab
Chimeric moab: ANSWER recombinant DNA linked with a human constant
and a murine variable
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller luzlinkuz. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $11.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79223 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now