Opt 6180 Adrenocorticosteroids, NSAIDs,
Antirheumatic, and Antihistamines questions with
correct answers
What hormones are secreted by the adrenal cortex? Correct Answer-
Cortisol (glucocorticoid), aldosterone (mineralocorticoid), and DHEA
(androgen)
What are the natural functions of cortisol? Correct Answer-Increase
plasma glucose levels and lipid metabolism. Suppress immune system.
Increase cardiac function. Under the influence of the HPA axis.
What are the natural functions of aldosterone? Correct Answer-Helps
regulate blood pressure and electrolyte balance. Anti-diuretic, increases
Na+ absorption in exchange for K+ secretion. Under the influence of the
RAAS system.
What are the short-to-medium acting glucocorticoids? Correct Answer-
Hydrocortisone, cortisone, prednisone, and prednisolone
What are the intermediate acting glucocorticoids? Correct Answer-
Triamcinolone and Fluprednisolone.
What are the long acting glucocorticoids? Correct Answer-
Betamethasone and dexamethasone
, What are the topical steroids that are used in the treatment of
dermatologic conditions, in order from low to high potency? Correct
Answer-Desonide, Triamcinolone, Fluticasone, Desoximetasone, and
Clobetasol
What are the characteristics of Addison's Disease? Correct Answer-This
is chronic adrenocortical insufficiency. Will have weakness, fatigue,
weight loss, hypotension, hyperpigmentation, and hypoglycemia.
Treated with a corticosteroid and a mineralocorticoid.
How is acute adrenocortical insufficiency treated? Correct Answer-With
large amounts of parenteral hydrocortisone, as well as correction of fluid
and electrolyte abnormalities.
What is Cushing's Syndrome? Correct Answer-This is adrenal
hyperplasia caused by an ACTH-secreting pituitary adenoma. Causes
hypersecretion of cortisol. Signs: moon face, buffalo hump, trunk
obesity, bruising, mental and CV disorders.
What are the mineralocorticoids used to treat an insufficiency? Correct
Answer-Aldosterone, Deoxycorticosterone, and Fludrocortisone
What are the major products of the cyclooxygenase pathway? Correct
Answer-Prostaglandins, thromboxane, and prostacyclin
What are the major products of the lipoxygenase pathway? Correct
Answer-Leukotrienes
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