BRS GI PHYSIOLOGY EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
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BRS PHYSIOLOGY
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BRS PHYSIOLOGY
BRS GI PHYSIOLOGY EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
1. Which of the following substances is released from neurons in the GI tract and produces smooth muscle relaxation?
(A) Secretin
(B) Gastrin
(C) Cholecystokinin (CCK)
(D) Vasoactive intestinal peptid...
1. Which of the following substances is released from neurons in the GI tract and
produces smooth muscle relaxation?
(A) Secretin
(B) Gastrin
(C) Cholecystokinin (CCK)
(D) Vasoactive intestinal peptide (VIP)
(E) Gastric inhibitory peptide (GIP)
1. The answer is D [II C 1]. Vasoactive intestinal peptide (VIP) is a gastrointestinal (GI)
neurocrine that causes relaxation of GI smooth muscle. For example, VIP mediates the
relaxation response of the lower esophageal sphincter when a bolus of food approaches
it, allowing passage of the bolus into the stomach.
2. Which of the following is the site of secretion of intrinsic factor?
(A) Gastric antrum
(B) Gastric fundus
(C) Duodenum
(D) Ileum
(E) Colon
, 2. The answer is B [IV B 1; Table 6-3; Figure 6-7]. Intrinsic factor is secreted by the
parietal cells of the gastric fundus (as is HCl). It is absorbed, with vitamin B12, in the
ileum.
3. Vibrio cholerae causes diarrhea because it
(A) increases HCO3- secretory channels in intestinal epithelial cells
(B) increases Cl- secretory channels in crypt cells
(C) prevents the absorption of glucose and causes water to be retained in the
intestinal lumen
isosmotically
(D) inhibits cyclic adenosine monophosphate (cAMP) production in intestinal
epithelial cells
(E) inhibits inositol 1,4,5-triphosphate (IP3) production in intestinal epithelial cells
3. The answer is B [V D 4 c]. Cholera toxin activates adenylate cyclase and increases
cyclic adenosine monophosphate (cAMP) in the intestinal crypt cells. In the crypt cells,
cAMP activates the Cl--secretory channels and produces a primary secretion of Cl-, with
Na+ and H2O following.
4. Cholecystokinin (CCK) has some gastrin-like properties because both CCK and
gastrin
(A) are released from G cells in the stomach
(B) are released from I cells in the duodenum
(C) are members of the secretin-homologous family
(D) have five identical C-terminal amino acids
(E) have 90% homology of their amino acids
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