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PHARM TOX: EXAM 1 QUESTIONS WITH COMPLETE SOLUTIONS
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PHARM TOX: EXAM 1 QUESTIONS WITH COMPLETE SOLUTIONS
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PHARM TOX: EXAM 1 QUESTIONS WITH COMPLETESOLUTIONS
_____ deals with how a drug alters the normal
physiocochemistry of the body. Correct Answer a.
Pharmacodynamics
A 32-year-old female visits her chiropractor because of
agitation, weight loss, and inability to sleep. When questioned
further, she reports increased appetite, increased bowel habits,
and irregular menstrual periods. Features on the physical exam
include warm skin, fine tremor of the hands, hyperreflexia, lid
lag, and moderately severe exophthalmos. Which of the
following disease processes is most likely manifesting itself?
a. A thyroid adenoma that is secreting thyroxine
b. Inappropriate release of hypothalamic secretion of
thyrotropin-releasing hormone
c. Grave's disease
d. Hashimoto Is disease Correct Answer c. Grave's disease
A beta one-receptor antagonist would be used to treat which of
the following conditions?
a. nasal congestion
b. diabetes mellitus
c. asthma
d. essential hypertension Correct Answer Essential
hypertension
A competitive antagonist
a. Combines with the same site on the receptor as does the
agonist
,b. Causes a parallel shift of the log dose-response curve to the
right
c. BothA and B are tue
d. Neither A or B is true Correct Answer Both A and B
A contraindication for a drug is defined as:
a. A pre-existing condition that significantly increases the risk of
side effects to a particular drug.
b. A pre-existing condition that would prevent the use of a
particular drug under all but the most desperate circumstances.
c. A condition such as vomiting when an antibiotic is given.
d. None of the above; there are no real contraindications for
drugs. Correct Answer b. A pre-existing condition that
significantly increases the risk of side effects to a particular drug
A direct acting choline-mimetic would have all but one of the
following actions.
a. miosis
b. bradycardia
c. decrease gut motility
d. diaphoresis
e. salivation Correct Answer c. decrease gut motility
A direct acting cholinomimetic would have all but one of the
following actions.
a. Mydriasis
b. Bradycardia
c. Increased gut motility
d. Diaphoresis
e. Salivation Correct Answer Mydriasis
,A dispersion of coarse particles of a drug in an aqueous vehicle
describes a:
a. solution
b. suspension
c. capsule
d. tablet Correct Answer b. Suspension
A drug in an inactive form and metabolized in the body into an
active form is called a:
A Rectal suppository
B. Placebo
C, Prodrug
D. Caplet
E. Prolonged Correct Answer c. Prodrug
A drug which inhibits the effect of acetylcholinesterase would
have all the following effects, EXCEPT:
a. Diaphoresis (perspiration)
b. Bradycardia
c. Increased gut motility
d. Pupillary dilation (mydriasis)
e. Increased respiratory secretions Correct Answer Pupillary
dilation (mydriasis)
A drug which inhibits the effects of ACHase would have all of
the following effects EXCEPT:
a. Diaphoresis
b. Bradycardia
c. Decreased gut motility
d. Pupillary constriction (miosis)
, e. Increased respiratory secretions Correct Answer c.
Decreased gut motility
A family member of yours is considering the possibility of
participating in the trial study of a relatively new drug which
produces a very selective blockage of beta-I adrenergic
receptors. Which of the following would be an absolute
contraindication for the use of this drug?
a. History of ventricular tachycardia
b. Peptic ulcer disease
c. peptic ulcer
d. History of congestive heart failure
e. Essential hypertension
f. All of the above Correct Answer c. History of congestive
heart failure
A hypertensive crisis might be seen with which of the following
drug classes?
a. Tricyclic antidepressants
b. Benzodiazepines
c. Phenothiazines
d. Monoamine oxidase inhibitors
e. Barbiturates Correct Answer d. Monoamine oxidase
inhibitors
A lowering blood pressure drug that blocks beta two receptors
would decrease peripheral resistance
true
false Correct Answer a. False (it would increase)
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