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PHAR 100 Midterm Exam with correct Answers
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PHAR 100 Midterm Exam with correct Answers
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PHAR 100 Midterm Exam with correctAnswers
9 iiSteps iiof iiDrug iiDiscovery iiProcess ii- iiAnswers ii-1. iiDrug iiDiscovery ii
2. iiPre-Clinical iiStudies ii
3. iiInitial iiClinical iiTrials ii
4. iiPhase iiI iiClinical iiTrials ii
5. iiPhase iiII iiClinical iiTrials ii
6. iiPhase iiIII iiClinical iiTrials ii
7. iiHealth iiCanada iireview
8. iiManufacturing
9. iiPost-Marketing iiSurveillance
What iiare iithe ii2 iitypes iiof iipre-clinical iitrials? ii- iiAnswers ii-Toxicology iiand
iiPharmacology
Efficacy ii- iiAnswers ii-Max. iipharmaceutical iiresponse iia iidrug iican iimake
Potency ii- iiAnswers ii-Amount iiof iidrugs iineeded iito iiproduce iia iispecific iiresponse
Therapeutic iiRange ii- iiAnswers ii-Concentration iibetween iiminimum iiconcentration iiand
iitoxicity
Pharmacokinetics ii- iiAnswers ii-Movement iiof iidrug iiinto, iithrough, iiand iiout iithe iibody
ADME ii- iiAnswers ii-absorption, iidistribution, iimetabolism, iiexcretion
Topical iiadministration ii- iiAnswers ii-on/thru iiskin/inhalation
Enteral iiadministration ii- iiAnswers ii-Mouth/rectum/sublingual/buccal
Parenteral iiadministration ii- iiAnswers ii-IV/muscle/subcutaneous
Bioavailability ii- iiAnswers ii-Fraction iiof iiadministration iidose iithat iireaches iiblood iiin
iiactive iiform
Teratogenesis ii- iiAnswers ii-Drug iiproduces iifetal iidefects
Therapeutic iiIndex ii- iiAnswers ii-measures iitoxicity. iiToxic iidose iiin ii50% iiof
iipop./effective iidose iiin ii50% iiof iipop.
primary iiexcitatory iiin iiCNS, iiglutamatergic iireceptor. iiimportant iifor iilearning ii- iiAnswers
ii-Glutamate
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