Mitochondrial membrane transport and the electron transfer chain:
The outer membrane contains porins, which are ......
channel proteins that allow diffusion of molecules of about less than 5,000
daltons
Porins:
beta-barrel transmembrane channel proteins found in gram + bacteria,
mitochondria, and chloroplasts
Inner membranes:
are impermeable to most molecules, especially to H+
what is the inner membrane of mitochondria made of?
70% proteins and 30% lipids
what are the components of the inner membrane of mitochondria?
- redox proteins of the ETC
- ATP synthase
- many carrier proteins
Redox proteins of the electron transfer chain consists of many protein and
coenzymes that create a ......
proton gradient as they pass electrons from NADH to O2
ATP synthase:
catalyzes the synthesis of ATP from ADP + P driven by flux of protons across
the inner mitochondrial membrane generated by the ETC
, ATP synthase structure has 2 regions:
Fo in the inner membrane and F1 in the matrix
What is the same in plants, animals, fungi, and chloroplasts?
ATP synthase
An ancestral version of ATP synthase occurs in .....
archaea
Many carrier proteins, such as phosphate translocases, ADP/ATP translocases,
pyruvate/H+ symporter, alpha-glycerol-P, malate shuttles, ad fatty acid
metabolism (B-oxidation) enzymes
Mitoplasm:
contains highly concentrated mixture of hundreds of enzymes, including those
required for the oxidation of pyruvate and fatty acids and for the citric acid
cycle
Inner membranes are folded into numerous ....
cristae
The inner membrane contains proteins that carry out .....
oxidative phosphorylation, including the electron transport chain and the ATP
synthase that makes ATP
The Outer membrane contains large channel-forming proteins called ......
porins
the outer membrane is permeable to ....
all molecules of 5,000 Da or less
Intermembrane space:
contains several enzymes that use the ATP passing out of the matric to
phosphorylate other nucleotides
the intermembrane space also contains proteins that are released during ....
apoptosis
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