ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE 12TH
EDITON
GERALYN FRANDSEN
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
Chapter 1, T...
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE 12TH
EDITON
GERALYN FRANDSEN
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated through
the bloodstream to their sites of action in various body tissues, and eventually eliminated
from the body. Curative agents are given to cure a disease process. In this case, paroxetine
hydrochloride will control the symptoms but not cure the disorder. Drugs with local effects,
such as sunscreen and local anesthetics, act mainly at the site of application. Paroxetine
hydrochloride is not administered parenterally. Parenteral agents are administered
subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A qclient q has qbeen qprescribed qan qantibiotic. qThis qmedication qis qa qnaturally qoccurring
substance qthat qhas qbeen qcheG mRicA
alDlyEm
SoBdOifOieSd.TWhaOt qM
.C is qanother qname qfor qthis qtype qof
qmedication?
A. Synthetic qdrug
B. Semisynthetic qdrug
C. Biotechnology qdrug
D. Prototype qdrug
ANS: q qB
Rationale: qSemisynthetic qdrugs q(e.g., qmany qantibiotics) qare q naturally qoccurring qsubstances
q that qhave qbeen qchemically qmodified. qSynthetic qdrugs qare qmore qstandardized q in qtheir
qchemical q characteristics, q more qconsistent q in qtheir qeffects, qand qless qlikely qto q produce
qallergic qreactions. q Biotechnology qdrugs qinvolve q manipulating qDNA qand qRNA qand
qrecombining qgenes qinto q hybrid q molecules qthat q can qbe q inserted qinto qliving qorganisms.
qPrototype qdrugs qare qthe qfirst q drug qof qa qparticular qgroup qto q be qdeveloped.
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