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Maryville University Pharmacology 615, chapters 1-4 Study Guide Solutions
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Maryville University Pharmacology 615, chapters 1-4 Study Guide Solutions early part of drug development - ANSWER-preclinical stage phase one clinical trials - ANSWER-establish biological effects as well as safe dosages and pharmacokinetics in a small number of healthy patients phase two clin...

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  • November 18, 2024
  • 15
  • 2024/2025
  • Exam (elaborations)
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  • maryville university pharmacology 615 chapters 1

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  • Maryville University NURS 615
  • Maryville University NURS 615

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Maryville University Pharmacology
615, chapters 1-4 Study Guide
Solutions

early part of drug development - ANSWER✔✔-preclinical stage


phase one clinical trials - ANSWER✔✔-establish biological effects as well as safe

dosages and pharmacokinetics in a small number of healthy patients


phase two clinical trials - ANSWER✔✔-new drug used to treat disease in a small

number of patients and establish the potential of the drug to improve outcomes


phase three clinical trials - ANSWER✔✔-compare the new medication to standard

therapy


two types of drug responses - ANSWER✔✔-quantal and graded


guanine nucleotide regulatory proteins (G proteins) - ANSWER✔✔-seven regions of

protein span the cell membrane to create a pocket for drugs to bind


drugs can act on one of three types of receptor sites (agonists/full agonists, antagonists,

partial antagonists) unless they are - ANSWER✔✔-of a type that do not act through

receptors. i.e. general anesthetics, sodium bicarbonate


Copyright ©SOPHIABENNETT 2025 ACADEMIC YEARALL RIGHTS RESERVED. Page 1/15

, metabolism - ANSWER✔✔-changing one chemical into another


first step in WHO process to prescribe - ANSWER✔✔-develop an accurate diagnosis


three types of treatment goals with medications - ANSWER✔✔-curative, symptom

relieving, preventative


homeostasis - ANSWER✔✔-the tendency of a cell, tissue, or the body not to respond to

drugs but instead to maintain the internal environment by adjust physiological

processes..


effects of route of administration are dependent on what 4 factors? - ANSWER✔✔-

compliance, bioavailability, onset of action, duration of action


half-life - ANSWER✔✔-time over which the drug concentration will decrease by half.


drug interactions - ANSWER✔✔-there are a limited number of drug-metabolizing

enzymes, and these enzymes can metabolize only one drug molecule at a time.


excretion - ANSWER✔✔-process by which the drugs are transferred from inside the

body to outside the body


which organ is the primary organ of excretion for most drugs? - ANSWER✔✔-kidneys


As many as___ percent of patients do not take their medications as prescribed, or do not

take them at all - ANSWER✔✔-50%




Copyright ©SOPHIABENNETT 2025 ACADEMIC YEARALL RIGHTS RESERVED. Page 2/15

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