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NURS 615 PHARM EXAM 1 MARYVILLE QUESTIONS AND ANSWERS 100% PASS
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NURS 615 PHARM EXAM 1 MARYVILLE QUESTIONS AND ANSWERS 100% PASS What factors are associated with clinical judgment when prescribing medications? - ANSWER-Prescribing a drug is based on a thorough assessment of the patient and the patient's environment. The determination of potential medical and...

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  • November 18, 2024
  • 16
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • nurs 615 pharm exam 1 maryville questions and answ

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  • Maryville University NURS 615
  • Maryville University NURS 615

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NURS 615 PHARM EXAM 1 MARYVILLE
QUESTIONS AND ANSWERS 100% PASS


What factors are associated with clinical judgment when prescribing medications? -

ANSWER✔✔-Prescribing a drug is based on a thorough assessment of the patient and

the patient's environment. The determination of potential medical and nursing

diagnoses, a review of the potential alternative therapies, specific knowledge about the

drug chosen, and the disease process it is going to treat, known as patient centered care.

The best therapy is usually the least invasive, least expensive, and the least likely to

cause adverse reactions


What are the criteria for choosing an effective drug? - ANSWER✔✔-Multiple drugs may

be able to treat a specific condition. You must consult nationally recognized guidelines

for disease management to determine the most effective drug.


How does hypoalbuminemia affect the process of prescribing? - ANSWER✔✔-Many

drugs that carry an electric charge are bound to albumin in the blood. The distribution

of the drug to target tissues may be affected if hypoalbuminemia is present.


What is the drug's half-life? - ANSWER✔✔-In clinical practice it takes about four to five

times the half-life for a drugs concentration to read steady state after a drug is started,

stopped or changed. Hal life is the amount of time for a drug to be half cleared.



Copyright ©SOPHIABENNETT 2025 ACADEMIC YEARALL RIGHTS RESERVED. Page 1/16

,What is meant by the onset of action, peak of action, duration of action of medications? -

ANSWER✔✔-The onset of action is the time between the drug administration and the

time that you see the drugs minimum effect. Onset is the first sign of a drugs

therapeutic effect. Peak of action is the time of the maximum concentration of the drug

in the blood. Duration of action is the onset of action and the metabolism of the drug

below the dose needed for an effect.


Explain first pass metabolism. - ANSWER✔✔-This occurs when the concentration of the

drug is greatly reduced before it reaches the systemic circulation. It is the portion of the

drug lost during absorption. Generally, occurs in the liver or gut wall. After a drug is

swallowed it is absorbed by the digestive system and enters the hepatic system. It is

then carried by the portal vein to the liver before it reaches the rest of the body. The

liver metabolizes many drugs to such an extent that only a small portion of the drug

reaches the rest of the body. bioavailability of the drug thus is greatly reduced by the

liver. Sublingual administration can bypass the first pass system plus it is also faster

than oral route.


What is a steady state? - ANSWER✔✔-The overall intake of a drug is fairly and

dynamic equilibrium with its elimination. Steady state is reached when the time of four

to five times the half-life is reached since the drug had been started.


What factors affect the drug's absorption? - ANSWER✔✔-Absorption involves several

steps. First the drug must be introduced via route of administration and the form of

medication like tablet or capsule. In IV or IM administration the absorption is less

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, variable and bioavailability is near 100%. IV administration is considered to lose no

portion of the drug. The fastest route of absorption is inhalation. Drugs must pass

through the epithelial cells of the GI tract to be absorbed by the circulatory system. Cell

membranes may affect the absorption of some drugs because they are made of lipid

bilayers that are semi permeable. This means only small uncharged solutes can pass

through the membrane. Whether or not a molecule is ionized affects the absorption,

since ionic molecules are charged. Solubility favors charged species. Permeability favors

neutral species. Some molecules have special channels to facilitate movement from the

lumen into the circulation. The Henderson Hasselbeck equation offers a way to

determine the portion that is ionized in a given pH. Weak acids will be present in their

nonionic form in the stomach because of the acidic pH and bases will be in their ionic

form. Nonionic species diffuse easier through cell membranes. Weak acids have a

higher absorption rate in the stomach. The opposite is true in the basic environment of

the stomach.


Identify drug metabolism and the role of the isoenzymes of the P450 system. -

ANSWER✔✔-CYPs are the major enzymes in drug metabolism. Must drugs undergo

deactivation by CYPs are directly facilitated secretion from the body. Many substances

are bioactivated by CYPs to form their active compound. Many drugs increase or

decrease the activity of CYPs isoenzymes either by inducing biosynthesis of an isozyme,

which is enzyme induction or by directly inhibiting the activity of CYP which is enzyme

inhibition. This is a major source of adverse drug reactions since changes in CYPs


Copyright ©SOPHIABENNETT 2025 ACADEMIC YEARALL RIGHTS RESERVED. Page 3/16

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