©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
Fnu 404 Anemias- b's, thiamin, riboflavin,
niacin, B6, pantothenic acid, biotin, vitamin
C Exam Study Guide.
Megaloblastic anemia - answer✔folate deficiency
pernicious anemia - answer✔vitamin B12 deficiency due to lack of intrinsic factor
homocysteine is increased with - answer✔folate and B12 deficiency
schilling test - answer✔distinguished pernicious anemia from other causes of B12 deficiency
folate deficiency anemia symptoms - answer✔weakness and pallor, degeneration of surface
mucosal tissue allowing mucosal ulceration and possible infection. sore tongue, GI
disturbances, diarrhea, and malabsorption
in folate deficiency anemia, there are decreased - answer✔WBCs and platelets
etiology of folate deficiency anemia - answer✔poor diet of low animal products, low green
vegetables, alcoholic, tea and toast of "elderly", poor intestinal absorption, increased metabolic
demands of late pregnancy, growth (early infancy), concurrent vit. C deficiency
good sources of folate include - answer✔dark green vegetables, liver, kidney, yeast
folate is easily destroyed by - answer✔inadequate handling, storage, and exposure to heat
sources of B12 - answer✔meat, milk, and eggs
etiology of B12 deficiency anemia - answer✔deficient in strictest vegetarian diet, lack of
intrinsic factor, heredity, gastrectomy, small bowel disease
food sources of thiamin - answer✔pork, whole grains, enriched cereals, liver, poultry, fish, eggs,
potatoes, legumes, nuts, dark green vegetables, brewer's yeast, and wheat germ
thiamin is easily - answer✔destroyed by heat and alkalinity
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, ©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
thiamin exists in - answer✔free form in plant foods
thiamin in animal foods is primarily as - answer✔thiamine diphosphate or thiamine
pyrophosphate
thiamin must be phosphorylated in - answer✔intestine
the absorption of thiamin is - answer✔usually high
thiamin phosphates are digested to yield - answer✔free thiamin
absorption of thiamin - answer✔occurs primarily in the jejunum, secondarily in the duodenum
and ileum
what reduces thiamin absorption? - answer✔alcohol
thiamin is transported by an - answer✔active, sodium- dependent mechanism
thiamin is transported _______ , bound to ______________ , or as ________________
__________________ - answer✔free, albumin, thiamine monophosphate
thiamin functions - answer✔energy production and nutrient metabolism (coenzyme role),
synthesis of pentoses and nicotinamide adenine dinucleotide phosphate (NADPH), nervous
system functions
functions of thiamin - answer✔metabolism and release of energy from carbs, oxidative
decarboxylation of a- ketoacids and 2-keto sugars, conversion of pyruvate to acetyl CoA,
reactions in the krebs cycle, anti- inflammatory, pentose phosphate pathway, membrane
conduction of nerve tissue, branched- chain amino acid metabolism
thiamin is excreted _____________ or _______________. - answer✔intact, catabolized
beriberi - answer✔thiamin deficiency (mental confusion, muscular problems, cardiac disorders,
CNS problems, anorexia, and fluid imbalance)
there is no tolerable upper intake level of - answer✔thiamin
wernicke- korsakoff syndrome - answer✔thiamin deficiency (clinical triad of confusion, ataxia,
and nystagmus)
riboflavin is important in - answer✔energy metabolism
what are the 2 coenzyme forms of riboflavin? - answer✔Flavin mononucleotide (FMN)
Flavin adenine dinucleotide (FAD), which are both involved in the transfer of electrons.
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