angiogenesis - ANSWER solid tumors create a new capillary network to "feed" themselves; formation of new blood vessels
staging - ANSWER where the cancer is located; extent of its invasion
grading - ANSWER looks at differentiation of the cancer cells
In chemotherapy what often limits the do...
NRSG 3100 Test 3 Questions &
Answers(RATED A)
angiogenesis - ANSWER solid tumors create a new capillary network to "feed"
themselves; formation of new blood vessels
staging - ANSWER where the cancer is located; extent of its invasion
grading - ANSWER looks at differentiation of the cancer cells
In chemotherapy what often limits the dose that can be administered? - ANSWER
myelosuppression (suppress blood cells and platelets)
some antiemetics prescribed for patients receiving chemotherapy? - ANSWER zofran
ativan
decadron
why do antineoplastics cause patients to vomit? - ANSWER because the vomiting
center in the medulla is triggered by these medications
what is a painful s/e of chemotherapy that causes GI bleeding and ulcers in the mouth
and esophagus? - ANSWER mucositis
what chemo medication causes cardiotoxicity and what should the nurse assess? -
ANSWER doxorubicin; ECG changes and assess for any signs of HF
what chemo medication is specifically know for causing pneumonitis? what should the
monitor with this medication? - ANSWER bleomycin; nurse needs to monitor patients
pulse ox and respiratory status, auscultating crackles in the lung fields, chest x-rays
may be necessary 2 to 3 time a week.
what chemo med is nephrotoxic? - ANSWER Cisplatin
what are some interventions for Cisplatin? - ANSWER increase intake
monitor I&O
Urine dipstick for SG and RBCs
what are the steps if your chemo line is no longer in the blood stream? - ANSWER -First
to prevent this, make sure you flush twice
-if extravasation occurs make sure to stop the infusion, elevated the limb, if the
neoplastic has a antidote use that, and lastly apply hot or cold per pharmacist
client teaching for chemo patients - ANSWER -avoid antipyretics
-increase fluid intake to 2-3 L/day
, -avoid crowded indoor areas
-cook food thoroughly
-avoid people with know infections and young children
cyclophosphamide - ANSWER -very broad spectrum of action
-used off label for immunosuppressive for prophylaxis of organ transplant rejection,
nephrotic syndrome, severe rheumatoid arthritis, lupus, and scleroderma
-hepatotoxic
a/e of cyclophosphamide - ANSWER -myelosuppression
-alopecia
-hemorrhagic cystitis
what medication is Mesna given with to prevent hemorrhagic cystitis? - ANSWER
cyclophosphamide
drug interactions with cyclophosphamide? - ANSWER -St. John's wort may increase the
toxic effects
-hepatotoxic meds
-additive immunosuppressive agents
-increases anticoagulation effects with other anticoagulants
methotrexate - ANSWER -used for severe RA that doesn't respond to NSAIDs and
psoriasis that is unresponsive to other treatments
BBW for methotrexate - ANSWER -combination with NSAIDs may cause severe or fatal
myelosuppression
-hepatotoxicity
-pulmonary toxicity
-dermatologic reactions
-ulcerative stomatitis and diarrhea
what is the rescue drug for a methotrexate toxicity? - ANSWER Levoleucovorin
doxorubicin - ANSWER -"the red devil"
-cardiotoxic
-make sure you get an ECHO to make sure there is no holes in the heart
-approved for use of AIDS related Kaposi's sarcoma
BBW for doxorubicin - ANSWER -SIGNIFICANT CARDIOTOXICITY, heart failure may
occur months to 6 months after therapy
-severe myelosupression may occur- major dose limiting toxicity, nadir 7 days
nadir treatment - ANSWER -infection precautions (abx)
-blood transfusion (bld and plts)
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