Kaplan & Sadock’s Synopsis of
Psychiatry Early-Onset Schizophrenia
Exam Questions and Correct Answers
Graded A+
What is childhood-onset schizophrenia? - Answer: Rare and progressive neurodevelopmental disorder.
When does the onset of psychotic symptoms occur? - Answer: Before 13 years old.
How does childhood-onset schizophrenia differ from adult-onset schizophrenia? - Answer: Increased
negative symptoms, severe social and cognitive consequences.
What brain structures show abnormalities in childhood-onset schizophrenia? - Answer: Cerebral cortex,
white matter, hippocampus, cerebellum.
What are some premorbid indicators of childhood-onset schizophrenia? - Answer: Social rejection, poor
peer relationships, academic trouble.
How does childhood-onset schizophrenia typically start? - Answer: With inappropriate affect or unusual
behavior.
What type of hallucinations are common in childhood-onset schizophrenia? - Answer: Auditory
hallucinations with critical commentary or command hallucinations.
Which types of hallucinations are more frequent in childhood-onset schizophrenia? - Answer: Visual,
tactile, and olfactory hallucinations.
What are some differential diagnoses for childhood-onset schizophrenia? - Answer: Autism spectrum
disorder, bipolar disorders, depressive disorders, drug-induced psychosis.
, What other disorders may present with psychotic phenomena in children? - Answer: Major depressive
disorder, bipolar I disorder.
How does autism spectrum disorder differ from childhood-onset schizophrenia? - Answer: Lacks core
features like hallucinations and delusions.
What factors influence the prognosis of childhood-onset schizophrenia? - Answer: Premorbid level of
functioning, age of onset, IQ, response to interventions, family support.
What factors are associated with poorer outcomes in childhood-onset schizophrenia? - Answer: Early
age at onset, comorbid developmental delays, lower IQ.
Why is accuracy and stability of the diagnosis important in childhood-onset schizophrenia? - Answer:
Some cases may later be identified as bipolar disorder.
What is the goal of management for childhood-onset schizophrenia? - Answer: Reduce symptoms,
improve functioning, enhance quality of life.
What are some treatment options for childhood-onset schizophrenia? - Answer: Antipsychotic
medications, psychosocial interventions, family therapy.
What is the role of antipsychotic medications in managing childhood-onset schizophrenia? - Answer:
Reduce positive symptoms, improve cognitive functioning.
What are some psychosocial interventions used in childhood-onset schizophrenia? - Answer: Individual
therapy, social skills training, school support.
How does family therapy benefit children with schizophrenia? - Answer: Improves family
communication, reduces stress, enhances coping skills.
What is the importance of early intervention in childhood-onset schizophrenia? - Answer: Can lead to
better outcomes and prevent long-term disability.
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