Kaplan & Sadock's Synopsis of
Psychiatry, 11th Ed. Chapter 12
Neurocognitive Questions and Correct
Answers Graded A+
How common are delusions in patients diagnosed with Alzheimer's Dementia? (Kaplan & Sadock
Synopsis, p 713) - Answer: 30-40%
How common are major depressive disorder in patients diagnosed with Alzheimer's Dementia? (Kaplan
& Sadock Synopsis, p 713) - Answer: 10-20%
What is Criteria A of Major or Mild Neurocognitive Disorder due to Alzheimer's Disease? (Kaplan &
Sadock Synopsis, p 714) - Answer: The criteria are met for a major or mild neurocognitive disorder
What is Criteria B of Major or Mild Neurocognitive Disorder due to Alzheimer's Disease? (Kaplan &
Sadock Synopsis, p 714) - Answer: There is insidious onset and gradual progression of impairment in one
or more cognitive domains (for mild) and at least two or more (for major)
Seizures are more common which subtype of Dementia? (Kaplan & Sadock Synopsis, p 714) - Answer:
Vascular Dementia
Psueudobulbar palsy. Dysarthria and dysphasia are mostly found in this subtype of Dementia (Kaplan &
Sadock Synopsis, p 714) - Answer: Vascular Dementia
This syndrome is characterized by drowsiness, confusion, ataxia, and accidental falls. This occurs in
demented patients when external stimuli, such as light and interpersonal orienting cues are diminished.
(Kaplan & Sadock Synopsis, p 714) - Answer: Sundowner Syndrome
What is the prevalence rate of Alcohol-Induced Persisting dementias? (Kaplan & Sadock Synopsis, p 715)
- Answer: 4%
, Focal neurological symptoms are more commonly seen in which subtype of dementia? (Kaplan & Sadock
Synopsis, p 715) - Answer: Vascular Dementia
What do you call brief episodes of focal neurological dysfunction lasting less than 24 hours (usually 5-15
minutes)? (Kaplan & Sadock Synopsis, p 715) - Answer: Transient Ischemic attacks
Depression-related cognitive dysfunction is also known known as this term? Patients with these have
more prominent depressive symptoms, more insight into their symptoms than do demented patients.
(Kaplan & Sadock Synopsis, p 715) - Answer: Pseudodementia
What is the average survival expectation (in years) for patients with Alzheimer's dementia? (Kaplan &
Sadock Synopsis, p 715) - Answer: 8 years with a range of 1-20 years.
How many (in percentage) of those with Dementia will have a reversible course if treatment is initiated
early? ((Kaplan & Sadock Synopsis, p 716) - Answer: 10-15%
What is the first step in the treatment of Dementia? (Kaplan & Sadock Synopsis, p 717) - Answer:
Verification of the diagnosis
Cholinesterase inhibitors reduce or increase activation of acetylcholine? (Kaplan & Sadock Synopsis, p
717) - Answer: Reduce
Tacrine is rarely used because of it's potential for which organ toxicity? (Kaplan & Sadock Synopsis, p
718) - Answer: Hepatotoxcicity
Which Dementia drug protects neurons from excessive amount of glutamate which is said to be
neurotoxic? (Kaplan & Sadock Synopsis, p 715) - Answer: Memantine
What are the 6 Cognitive Domains? (DSM5, p 593-595) - Answer: Complex attention, Executive function,
Learning and memory, Language, Perceptual motor and Social cognition
This Neurocognitive disorder is marked by short-term confusion and cognition (Kaplan & Sadock
Synopsis, p694) - Answer: Delirium
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