UNE Biochemistry Unit 4 Exam
Questions and Answers
Which of the following amino acids is considered non essential because it is generated
by the urea cycle?
A. arginine
B. lysine
C. asparagine
D. glutamine
E. histidine - Answers -arginine
The urea cycle takes place in which of the following subcellular locations?
A. the cytosol and the mitochondria
B. the mitochondria only
C. the cytosol only - Answers -the cytosol and the mitochondria
Ubiquitination is a means of targeting a protein for which of the following cellular
proceses?
A. Digestion
B. Proteasomal degradation
C. Storage
D. Protein translation - Answers -Proteasomal degradation
The reaction of ammonia with α-ketoglutarate is catalyzed by _________ and requires
_________ as a reactant.
A. glutamate dehydrogenase; ATP
B. glutamate dehydrogenase; NADH or NADPH
,C. glutamate synthetase; NADH or NADPH
D. glutamate synthetase; ATP - Answers -glutamate dehydrogenase; NADH or NADPH
Most enzymes involved in protein digestion require cleavage for activation. These
proteins are secreted as inactive protein forms called:
A. zymogens
B. unfolded polypeptides
C. dimers
D. activated forms - Answers -zymogens
Which of the following enzymes is regulated by N-acetyl glutamate (NAGs)?
A. CPS II
B. ornithine transcarbamylase
C. arginosuccinate lyase
D. CPS I - Answers -CPS I
Which of the following enzymes will be active in both the fed and fasted states?
A. Glutaminase
B. Pyruvate kinase
C. Hormone sensitive lipase
D. Glycogen synthase - Answers -Glutaminase
Which of the following enzymes is correctly paired with its activator?
A. N-acetylglutamate synthtase; arginine
B. Carbamoyl phosphate synthetase I; ATP
C. Glutaminase; citrate
D. arginase; NADH - Answers -N-acetylglutamate synthtase; arginine
Which of the following statements is consistent with nitrogen transport in the fasted
state?
, A. Glutaminase will be active
B. The urea cycle will be inactive
C. Hepatic glutamate dehydrogenase will primarily produce glutamate
D. Transport of alanine from skeletal muscle will be reduced. - Answers -Glutaminase
will be active
In the case of a urea cycle deficiency, which of the following amino acids may become
essential?
A. glutamine
B. arginine
C. alanine
D. aspartate - Answers -arginine
The glucose alanine cycle is a method of transferring ammonia from the skeletal muscle
to the liver. In this process the non-toxic carrier of ammonia is which of the following
compounds?
A. glutamine
B. pyruvate
C. alanine
D. urea - Answers -alanine
Pepsinogen is activated by which of the following mechanisms or enzymes?
A. Pepsinogen is activated by trypsin
B. Pepsinogen is activated by enteropeptidase
C. A change in pH catalyzes the activation of pepsinogen to pepsin
D. Pepsinogen is activated by elastase - Answers -A change in pH catalyzes the
activation of pepsinogen to pepsin
The process of autophagy is defined as which of the following processes?
A. Recycling of proteins under conditions of cellular need or starvation
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