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Week 12 UNE biochem Exam Questions and Answers
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Week 12 UNE biochem Exam Questions and Answers
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Week 12 UNE biochem Exam Questionsand Answers
Acetyl CoA - Answers -all 27 carbons in cholesterol synthesis come from
cytosol - Answers -the location for cholesterol synthesis.
2-mevalonate - Answers -condensation of acetyl CoA to ____ is our initial reaction in
cholesterol synthesis and the regulatory step
Bile acid/cholesterol/mevalonate - Answers -HMG CoA reductase is negatively
regulated by:
HMG CoA reductase - Answers -Regulatory enzyme of cholesterol synthesis
HMG CoA reductase - Answers -statins target the enzyme:
Inactivate - Answers -effect of phosphorylation on HMG CoA reductase
CETP - Answers -Exchanges TAGs from VLDL with cholesteryl ester from HDL
Primary bile acids - Answers -cholic and chenodeoxycholic acid are
Ileum - Answers -site of bile reabsorption (secondary bile acids)
Citrate lyase - Answers -cleaves citrate back into OAA + acetyl CoA (which contributes
to pool of acetyl CoA in cytosol used for FA and cholesterol synthesis)
LDL - Answers -IDL is further metabolized into
clathrin-coated pits - Answers -LDL receptors are found within ____ on the cell surface.
ACAT - Answers -the unesterified pool of cholesterol (↑ by uptake of LDL) can be
esterified to CE by the enzyme
ABC transporters (ABCG1/ABC1) - Answers -the unesterified pool of cholesterol (↑ by
uptake of LDL) can be transferred to HDL via
Alpha 6 hydroxylase - Answers -regulatory enzyme of bile acid synthesis
Bile acid - Answers -Bile acid synthesis is inhibited by:
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