Advanced Pharmacology Final Questions With Complete Solutions
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Advanced Pharmacology Final Questions
With Complete Solutions
Which statement is correct regarding the difference between acetaminophen and naproxen?
A. Acetaminophen has more anti-inflammatory effects compared with naproxen.
B. Acetaminophen has more Gl side effects but less effects on bleedi...
Advanced Pharmacology Final Questions
With Complete Solutions
Which statement is correct regarding the difference between acetaminophen and naproxen?
A. Acetaminophen has more anti-inflammatory effects compared with naproxen.
B. Acetaminophen has more Gl side effects but less effects on bleeding compared with naproxen.
C. Acetaminophen has less risk for CV events compared with naproxen.
D. Acetaminophen has fewer antipyretic effects than
naproxen. C. Acetaminophen has less risk for CV events compared with naproxen.
Which statement correctly describes the proposed mechanism of cardioprotection from low-dose
aspirin?
A. Aspirin preferentially inhibits COX-2 to lead to a relative reduction in thromboxane ~ levels.
B. Aspirin preferentially inhibits COX-1 to lead to a relative reduction in thromboxane ~ levels.
C. Aspirin preferentially inhibits COX-2 to lead to a relative reduction in prostacyclin levels.
D. Aspirin preferentially inhibits COX-1 to lead a relative reduction in prostacyclin levels.
B. Aspirin preferentially inhibits COX-1 to lead to a relative reduction in thromboxane ~
levels.
, Advanced Pharmacology Final Questions
With Complete Solutions
Which statement correctly describes the pathophysiologic actions of prostaglandins at a target
tissue?
A. Promote vasoconstriction in the kidneys.
B. Promote sodium and water retention in the kidneys.
C. Decrease secretion of mucus at the lining of the
stomach.
D. Decrease secretion of gastric acid in the stomach D. Decrease secretion of gastric acid
in the stomach
Which prostaglandin agent can be used to maintain the patency of the ductus arteriosus in
neonates with congenital heart problems while awaiting surgery?
A. Misoprostol
B. Epoprostenol
C. Bimatoprost
D. Alprostadil D. Alprostadil
, Advanced Pharmacology Final Questions
With Complete Solutions
A 34-year-old woman with RA is planning for pregnancy. Which RA agents are absolutely
contraindicated
in pregnancy?
A. Abatacept and rituximab
B. Adalimumab and certolizumab
C. lnfliximab and etanercept
D. Methotrexate and leflunomide D. Methotrexate and leflunomide
Which agent for RA competes with CD28 to prevent full T-cell activation?
A. Sarilumab
B. Abatacept
C. Golimumab
D. Adalimumab B. Abatacept
Which statement correctly represents the mechanism of action of tofacitinib in the treatment of
RA?
, Advanced Pharmacology Final Questions
With Complete Solutions
A. TNF-a inhibitor
B. Janus kinase inhibitor
C. IL-6 receptor blocker
D. Dihydrofolate reductase inhibitor B. Janus kinase inhibitor
A 54-year-old man with gout is found to have an issue with renal excretion of uric acid. Which
drug is an oral agent that would target the cause of his acute gout attacks?
A. Allopurinol
B. Febuxostat
C. Probenecid
D. Pegloticase C. Probencid
A 64-year-old man presents with signs and symptoms of an acute gouty flare. Which strategy is
the least likely to acutely improve his gout symptoms and pain?
A. Naproxen
B. Colchicine
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