Advanced Pharmacology Final Questions With Complete Solutions
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Advanced Pharmacology Final Questions
With Complete Solutions
Anti-inflammatory drugs A drug that prevent or limit tissue and blood vessel responses to
injury or invasion. Categories include: corticosteroids. Nonsteroidal, anti-inflammatory, antihistamines, and leukotriene inhibitors.
Non-st...
Advanced Pharmacology Final Questions
With Complete Solutions
Anti-inflammatory drugs A drug that prevent or limit tissue and blood vessel responses to
injury or invasion. Categories include: corticosteroids. Nonsteroidal, anti-inflammatory, anti-
histamines, and leukotriene inhibitors.
Non-steroidal Anti-inflammatories (NSAIDs) Anti-inflammatory drugs that are not
similar to cortisol but prevent or limit the tissue and blood vessel responses to injury or invasion
by slowing the production of one or more inflammatory mediators. Used to treat fever, arthritis,
gout, lupus, pain, and blood clots it stops the action of the Cyclo-Oxygenase (Cox) enzyme. Side
effects: bleeding, gi ulcer or pain, fluid retention, hypertension
Non-steroidal Anti-inflammatories (NSAIDs) drugs include: Cox one inhibitors Salicylic
or aspirin ,Propionic Acid or Ibuprofen, Celecoxib commonly known as Celebrex also a cox 2
inhibitor
Cox-1 Reduce platelet clumping and blood clotting increase risk for bleeding in response
to slight injuries irritated stomach
Cox-2 Have fewer side effects than cox 1 do not affect platelet action and blood clotting.
, Advanced Pharmacology Final Questions
With Complete Solutions
Celebrex Made from sulfa drug type check for allegies
Before giving NSAIDs Check to see if need to be given parenterally using toradol. Ask if
pt is allergic to sulfa drugs. Ask pt if they had any problems with aspirin or any over the counter
NSAIDs take with meal or milk tell pt not to chew check BP NSAIDs interfere with
hypertension meds.
NSAIDs teaching Check bm for blood report symptoms asap check gums daily for
bleeding let dentist know before procedure do not take with Coumadin weigh twice a week
inform if more than 3lbs in a week
Diphenhydramine (Benadryl ) Reduces inflammation by preventing the inflammatory
mediators from binding to its receptor. SE: sleepiness, dry mouth, blurred vision, tachycardia,
and urinary retention. AE: seizures and worsens glaucoma which leads to blindness.
Before giving antihistamine Ask patient if they are being treated for glaucoma, high BP,
or prostate enlargement because it is contraindicated in pt with these problems check other drugs
such as muscle relaxer wait 4 hours of each drug
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