Exam (elaborations)
AALAS LAT QUESTIONS AND ANSWERS 2024
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Exam of 59 pages for the course LAT at LAT (AALAS LAT)
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AALAS LATWhat is research?
a. A protocol that is approved by the Institutional Animal Care and Use Committee
(IACUC)
b. An investigation into the practices of the facility
c. A systematic investigation to establish facts
d. A program that was developed to help researchers learn new skills - answerc. A
systematic investigation to establish facts
What is the first step in scientific research?
a. Create a research design
b. Define the question to be investigated
c. Collect data
d. Report the conclusions - answerb. Define the question to be investigated
Which of the following reviews the animal use protocols of research projects to ensure
compliance with all relevant federal, state, and local laws, regulations, and institutional
policies on animal welfare?
a. National Institutes of Health (NIH)
b. United States Department of Agriculture (USDA)
c. National Science Foundation (NSF)
d. Institutional Animal Care and Use Committee (IACUC) - answerd. Institutional Animal
Care and Use Committee (IACUC)
What does the Institutional Animal Care and Use Committee (IACUC) have the authority
to do?
a. Approve animal care and use protocols
b. Deny an investigator permission to begin a research project
c. Stop a previously approved protocol
d. All of the above - answerd. All of the above
IACUCs are mandated by which of the following?
a. Federal mandate
b. City ordinance
c. State law
d. Institutional policy - answera. Federal mandate
Which mandate requires five Institutional Animal Care and Use Committee (IACUC)
members?
a. Guide for the Care and Use of Laboratory Animals
b. Animal Welfare Regulations
,c. Good Laboratory Practice Regulations
d. Public Health Service (PHS) Policy - answerd. Public Health Service (PHS) Policy
What step must occur before a research study using animals begins?
a. An animal use protocol needs to be submitted to the Institutional Animal Care and
Use Committee (IACUC).
b. An animal use protocol must be received by the Institutional Animal Care and Use
Committee (IACUC).
c. An animal use protocol must be approved by the Institutional Animal Care and Use
Committee (IACUC).
d. An animal use protocol needs to be examined by the Institutional Animal Care and
Use Committee (IACUC). - answerc. An animal use protocol must be approved by the
Institutional Animal Care and Use Committee (IACUC).
The Animal Welfare Regulations require that protocols for United States Department of
Agriculture (USDA)-covered species may only be approved for how long?
a. 6 months
b. 1 year
c. 2 years
d. 3 years - answerb. 1 year
How often do the Animal Welfare Regulations require the IACUC to monitor the animal
care and use program through reviews of the program and routine inspections of the
animal facilities?
a. At least every 3 months
b. At least every 9 months
c. At least every 6 months
d. At least one per each year - answerc. At least every 6 months
What is the name of the program that helps to ensure that IACUC-approved procedures
are being followed?
a. Postapproval monitoring program
b. Procedure approval monitoring program
c. Protocol approval monitoring program
d. Preapproval monitoring program - answera. Postapproval monitoring program
How many years does a typical grant provide money for funding of a research project?
a. 1-2
b. 3-5
c. 6-8
d. 10 - answerb. 3-5
What is a grant application?
a. Paperwork used to request more animals in a study
b. Paperwork used to request the hiring of more staff
c. Paperwork used to request approval of a protocol
,d. Paperwork used to request research money - answerd. Paperwork used to request
research money
How many Institutional Animal Care and Use Committee (IACUC) members are
required by the Animal Welfare Regulations (enforced by the United States Agricultural
Department)?
a. 2
b. 3
c. 4
d. 5 - answerb. 3
How much of the tail may be snipped with performing a tail transection?
a. 1-2 mm
b. 1-2 inches
c. 2-3 mm
d. 2-3 inches - answera. 1-2 mm
Before a new drug is tested on human subjects, the drug is tested on animals in a
phase that is called __________ testing.
a. clinical
b. preclinical
c. experimental
d. in vitro - answerb. preclinical
What information is NOT provided in a grant application?
a. Any preliminary data and results that are available
b. Thorough review of relevant literature
c. Detailed description of the research goals
d. Criminal background check on the individuals requesting the grant - answerd.
Criminal background check on the individuals requesting the grant
Which animals are NOT required by law to be accompanied by a health certificate when
being shipped?
a. Dogs
b. Cats
c. Laboratory mice
d. Nonhuman primates - answerc. Laboratory mice
Which organization uses the Guide for the Care and Use of Laboratory Animals (the
Guide) as one of its standards for the accreditation of laboratory animal programs?
a. Institutional Animal Care and Use Committee (IACUC)
b. Public Health Service (PHS)
c. National Science Foundation (NSF)
d. Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) -
answerd. Association for Assessment and Accreditation of Laboratory Animal Care
(AAALAC)
, If animals are to be euthanized at the end of a study, the method of euthanasia must be
in accordance with the guidelines set up by the ____________.
a. United States Agricultural Department (USDA)
b. National Institutes of Health (NIH)
c. Public Health Service (PHS)
d. American Veterinary Medical Association (AVMA) - answerd. American Veterinary
Medical Association (AVMA)
In the Guide, what word is used to describe aspects of an animal care program that are
strong recommendations?
a. Must
b. Could
c. Should
d. Would - answerc. Should
If an animal was used in teaching, research, experiments, or tests conducted that cause
no pain or distress and thus did not require the use of pain-relieving drugs, what United
States Agricultural Department (USDA) pain category would this describe?
a. B
b. C
c. D
d. E - answerb. C
Which of the following describes what a facility must do to comply with the Animal
Welfare Act (AWA)?
a. Animal Welfare Assurance
b. Public Health Service Policy
c. Animal Welfare Regulations
d. Ag Guide - answerc. Animal Welfare Regulations
What is a quality assurance unit responsible for ensuring compliance with?
a. Animal Welfare Regulations (AWR)
b. Public Health Service (PHS) Policy
c. The Guide
d. Good Laboratory Practices (GLPs) Regulations - answerd. Good Laboratory
Practices (GLPs) Regulations
Which of the following is NOT required by Public Health Service (PHS) Policy?
a. An Institutional Animal Care and Use Committee (IACUC) review of all protocols
b. At least three Institutional Animal Care and Use Committee (IACUC) members
c. An animal program review every 6 months
d. The use of the Guide for all animal use programs receiving federal research funds -
answerb. At least three Institutional Animal Care and Use Committee (IACUC) members
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