NUR 354 Pharmacology II Module 2
Shock, Hematopoietic, Neoplastic Drugs
Exam Questions and Answers
Blood or blood products - Answer-What drugs are administered to restore fluid volume
when more than 30% of fluid volume is lost?
replace plasma volume and supply red blood cells - Answer-MOA of blood/blood
products
whole blood, plasma protein fraction, fresh-frozen plasma, packed red blood cells -
Answer-What are the components of blood/blood products?
maintain plasma osmotic pressure; transport substances through blood - Answer-MOA
of colloid agents
Plasma volume expanders - Answer-What are colloid agents also called?
restoration of plasma volume and blood proteins - Answer-Primary use of colloid agents
normal human serum albumin, plasma protein fraction, serum globulins - Answer-What
are examples of blood colloids?
Dextran, hetastarch - Answer-What are examples of nonblood-product colloids?
can readily leave blood and enter cells to replace fluids that have been lost; promote
urine output - Answer-MOA of crystalloids
True - Answer-True or false: crystalloid concentrations resemble the concentrations of
plasma
normal saline, lactated ringer's, PlasmaLyte, hypertonic saline, D5W - Answer-What are
examples of crystalloids?
hypertonic, hypotonic, isotonic - Answer-What are the three classifications of
crystalloids?
normal serum albumin - Answer-Prototype for Colloid Agent (Fluid Replacement Agent)
maintain plasma osmotic pressure; transport substances through blood - Answer-MOA
of normal serum albumin
allergies; protein overload - Answer-Adverse effects of normal serum albumin
, act directly on alpha-adrenergic receptors to raise blood pressure - Answer-MOA of
Vasoconstrictors/Vasopressors for shock
True - Answer-True or false: vasoconstrictors/vasopressors have positive inotropic
effects
treat shock and cardiac arrest - Answer-Primary use for vasoconstrictors/vasopressors
dopamine, norepinephrine, phenylephrine, epinephrine - Answer-Examples of
vasoconstrictors/vasopressors
norepinephrine (Levophed) - Answer-Prototype for vasoconstrictors/vasopressors
to act directly on alpha-adrenergic receptors to raise blood pressure; also have positive
inotropic effects - Answer-MOA of norepinephrine
vasopressors strengthen heart contractility (stronger heart contractions), strengthening
cardiac output and help organs get blood and oxygen that they need to survive -
Answer-What does it mean that vasopressors have positive inotropic effects?
nonselective adrenergic agonist - Answer-Pharmacologic class of norepinephrine
(Levophed)
vasopressor - Answer-Therapeutic class of norepinephrine (Levophed)
phentolamine - Answer-If extravasation of norepinephrine occurs, what medication can
you administer as an antidote?
immediate - Answer-Onset of norepinephrine
1-2 min - Answer-Peak of norepinephrine
1-2 min - Answer-duration of norepinephrine
alpha and beta blockers (may antagonize the drug's vasopressor effects); ergot
alkaloids and tricyclic antidepressants may potentiate vasopressor effects; use with
MAOIs may lead to acute hypertensive crisis - Answer-Drug interactions with
norepinephrine
increase strength of myocardial contraction; increase cardiac output - Answer-MOA of
inotropic drugs for shock
treat hypovolemic shock and cardiogenic shock - Answer-Primary use of inotropic drugs
True - Answer-True or false: MOA of inotropic drugs are dose dependent
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