Amygdala function Right Ans - Responsible for the response and memory
of emotions, especially fear
common finding on imaging for pts with anxiety Right Ans - hyperactive
and enlarged amygdalas
PTSD Right Ans - A disorder in which a person has lingering memories,
nightmares, and other symptoms for weeks after a severely threatening,
uncontrollable event
Treatment of PTSD Right Ans - CBT and SSRIs
effects of serotonin on the body Right Ans - mood, sleep, appetite
regulation
treatment for acute attack of anxiety/panic Right Ans - benzos
dissociation Right Ans - loss of memory, identity, or ones sense of self
self Right Ans - unique identity- one that is comprised of an individuals
thoughts behaviors and feelings and memory
Types of Dissociative Disorders Right Ans - dissociative identity disorder,
dissociative amnesia, depersonalization/derealization disorder, dissociative
fugue
onset of dissociative disorder/episode Right Ans - usually precipitated by a
stressful life event or personal problem, frequently associated with childhood
abuse, acute adult trauma, substance abuse and major mood disorders
dissociative amnesia Right Ans - potentially reversible memory
impairment that primarily affects autobiographical information- not ordinary
forgetfulness- pt is aware of memory issue but not bothered by it
, types of memory Right Ans - autobiographical memory, semantic memory
and episodic memory
autobiographical memory Right Ans - the memory for events and facts
related to one's personal life story
semantic memory Right Ans - memory of objects, facts, and concepts,
including words and their meanings, such as learning the skill of reading
episodic memory Right Ans - the collection of past personal experiences
that occurred at a particular time and place
procedural memory Right Ans - the gradual acquisition of skills as a result
of practice, or "knowing how" to do things
epidemiology of dissociative amnesia Right Ans - about 10%, females more
than males, most common type of dissociative disorder, increased incidence
with comorbid major depressive disorder and anxiety disorder, younger
adults more than older adults
triggers of dissociative amnesia Right Ans - environmental-trauma,
neurobiological-temporal/hippocampal and occipital lobe areas
Prazosin Right Ans - alpha 1 antagonist,
treatment for ptsd related nightmares or disturbed arousals Right Ans - a
trial of prazosin
rationale for prazosin Right Ans - crosses blood brain barrier, nonsedating
agent, nonadrenergic, alpha 1 blocker
Doxasosin Right Ans - another alpha 1 blocker- crosses blood brain barrier
weakly- has potential long term effect for overall treatment of ptsd (not just
nightmares)
dosing of prazosin Right Ans - avoid subtherapeutic dosages, titration takes
time, 2 protocolos- one for women and one for men
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