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Rafi Endocrine - Questions And Correct Answers
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Rafi Endocrine - Questions And Correct Answers
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Rafi Endocrine - Questions And Correct AnswersA patient presents to you with tremors, sweating, weight loss despite
increased appetite. they complain of feeling tired and occasional feel
paplitations. on examination their hands are warm and sweaty, and they have
pretibial myxoedema.
What is the most likely cause of the patients symptoms
Grave's Disease
Hashimotos
Toxic Adenoma
Toxic Multinodular Goitre Right Ans - Graves Disease
Raised serum T4 and T3 will cause which of the following
Raised TSH
Raised TRH
Low TSH
Hypothyroidism Right Ans - Low TSH
Which of the following is not seen in toxic multinodular goitre
Exophthalamos
Cardiac Arrhythmia
Heart Failure
Weight loss Right Ans - Exophthalamos
A 51-year-old man presents to A&E with nausea and vomiting. His wife who
attends with him remarks that earlier in the day he had a terrible headache,
which felt as if he had 'been hit on the head with a baseball bat'. She told him
to get some rest and on his way to the door he walked into a coffee table. He
has a medical history of hypertension. His current blood pressure is 82/46
mmHg. On inspection the patient appears confused, weak and sweaty. On
examination he has a third-nerve palsy and bitemporal hemianopia. What is
the most likely diagnosis?
A. Sheehan's syndrome
B. Ruptured craniopharyngioma
,C. Pituitary macroadenoma
D. Pituitary microadenoma
E. Pituitary apoplexy" Right Ans - E
"
The patient's blood tests show hypoglycaemia,
hypocortisolaemia and low ACTH. What is the most appropriate action?
A. IV glucose
B. Transsphenoidal surgery
C. IV hydrocortisone
D. Oral prednisolone
E. IV dexamethasone" Right Ans - C
"
Which hormone is responsible for the sequelae of
Cushing's disease?
A. ACTH
B. LH
C. CRH
D. Prolactin
E. Aldosterone" Right Ans - A
"
Which of the results would be seen if Graves' disease is
the cause?
T3 T4 TSH Thyroglobulin
A. Raised Raised Raised Raised
B. Raised Raised Low Raised
C. Low Low Normal Normal
D. Raised Raised Low Low
E. Raised Low Raised Normal" Right Ans - B
"
The presence of thyroid receptor stimulating hormone
antibodies (TRAb) is seen in which one of the following?
,A. Hashimoto's thyroiditis
B. De Quervain's thyroiditis
C. Graves' disease
D. Primary atrophic hypothyroidism
E. Thyroid hormone resistance syndrome" Right Ans - C
"
A 34-year-old man presented to A&E with severe heart palpitations and chest
pain. The man's history reveals that he was recently at his GP complaining of
some mild palpitations, weight loss and agitation. The GP suspected
hyperthyroidism and ordered thyroid function tests but the results were not
back yet. His wife says he also had a fever and cough over the last few days. On
examination, the patient was found to be sweaty and had a tachycardia
(approximately 164 bpm) with an irregular rhythm. The patient's mental state
has also been deteriorating since he arrived. The doctor suspects a thyroid
storm due to the infection. What is the most appropriate immediate next step
with this patient's management?
A. Treatment with b-blocker and carbimazole
B. Treatment with antibiotics for the precipitating
infection
C. A technetium scan to confirm thyroid storm
D. Start radioiodine therapy
E. A partial thyroidectomy" Right Ans - A
"
What could be another possible precipitant of a thyroid
storm in a patient with hyperthyroidism?
A. Cushing's syndrome
B. Recent thyroid surgery
C. A myocardial infarction (heart attack)
D. Hyperglycaemia
E. Excess b-blocker treatment" Right Ans - B
"
A 35-year-old woman was referred to the hospital by her GP with polyuria,
polydipsia and altered sensations in her limbs that has been progressively
, worsening over the last 3 weeks. The hospital rules out type 2 diabetes but
investigations reveal she is hypertensive (154/80 mmHg) as well as
hypokalaemic and alkalotic. The doctor diagnoses Conn's syndrome. What is
the cause of Conn's syndrome?
A. Cortisol and aldosterone deficiency
B. ACTH-secreting tumour
C. Adrenaline-secreting tumour
D. Aldosterone-secreting tumour
E. Chronic excessive cortisol secretion Right Ans - D
What is the most common cause of secondary
hyperaldosteronism?
A. Excessive diuretic therapy
B. Ectopic ACTH secretion
C. Nephritic syndrome
D. Congenital adrenal hyperplasia
E. Acute adrenal cortical failure" Right Ans - A
"
A 42-year-old male was admitted to the endocrinology ward with increasing
weight, central obesity and depression. He also has been having erectile
dysfunction for the last month. Cushing's disease is the suspected cause and
an overnight dexamethasone suppression test is ordered to confirm. What is
the underlying cause of Cushing's disease?
A. Adrenal adenoma
B. Pituitary adenoma
C. Iatrogenic, i.e. steroid treatment
D. Ectopic ACTH
E. Primary hyperaldosteronism" Right Ans - B
"
What is the most appropriate treatment of cushings disease?
A. An oral glucocorticoid
B. Intramuscular recombinant human growth hormone
C. Stop all current steroid therapy
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