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UNE Medical Biochemistry Midterm Review Questions And Answers

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UNE Medical Biochemistry Midterm Review Questions And Answers Glycolysis High levels of activity of the non-oxidative portion of the pentose phosphate pathway will directly produce intermediates of which of the following pathways? Glucose 6-phosphate dehydrogenase The major regulatory step of ...

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  • November 23, 2024
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  • UNE Biochemistry
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UNE Medical Biochemistry Midterm Review
Questions And Answers

Glycolysis High levels of activity of the non-oxidative portion of the pentose phosphate

pathway will directly produce intermediates of which of the following pathways?




Glucose 6-phosphate dehydrogenase The major regulatory step of the pentose phosphate

pathway is catalyzed by which enzyme?




VLDL particles Insulin stimulates fatty acid synthesis in the liver. These fatty acids are

transported to the adipose tissue as which of the following?




Free fatty acids A young woman goes to work without eating breakfast and skips lunch. In

this scenario, which of the following pathways is providing substrates used to generate ATP in

the liver?




Glucagon Caffeine is a natural inhibitor of phosphodiesterase. If you were to consume a

large amount of coffee you would likely see a prolonged response to which of the following

stimulants or hormones?

,UNE Medical Biochemistry Midterm Review
Questions And Answers
They enhance transcription when bound to receptors A teenage female presenting with

lack of menstruation (amenorrhea) is found to have a dysfunctional steroid receptor characteristic

of androgen insensitivity syndrome. Which of the following statements accurately describes

steroid hormones?




Intracellular receptors Steroid hormones bind which of the following types of receptors?




They are specific to a chemical messenger Which of the following is a characteristic of all

receptors?




Free fatty acids What is the primary oxidized fuel for skeletal muscle in the fasted state?




Cyclic-AMP response element binding protein (CREB) cAMP elicits multiple cellular

responses. The effects of cAMP on gene transcription are directly mediated by which of the

following DNA binding proteins?




GLUT4 An individual is recently diagnosed with Type 2 diabetes. In this individual,

hyperglycemia may in part be due to inactivity of which of the following glucose transporters on

skeletal muscle?

, UNE Medical Biochemistry Midterm Review
Questions And Answers

Adenylyl cyclase Glycogen degradation in the liver can be enhanced by elevated glucagon

and the activation of a Gαs receptor. The initial step in this cascade involves which of the

following second messengers or active enzymes?




2 Which of the following combinations of compounds is required to fully activate

pyruvate carboxylase (+ indicates compound is necessary; - indicates compound is not

necessary)?




1. Biotin + Acetyl-CoA + Oxaloacetate + Malate -

2. Biotin + Acetyl-CoA + Oxaloacetate - Malate -

3. Biotin - Acetyl-CoA + Oxaloacetate + Malate +

4. Biotin - Acetyl-CoA - Oxaloacetate + Malate +




Acetyl-CoA Which of the following compounds is not a substrate for gluconeogenesis?




Pyruvate carboxylase deficiency A 1-month-old boy is brought to the emergency

department in a coma after sleeping through the night and failing to awaken in the morning. He

is given intravenous glucose and awakens. Serum levels of pyruvate, lactate, and alanine are

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