HIV EIA (3rd generation immunoassay)
can use urine, saliva, or serum (most accurate), need to wait until 12
weeks post exposure to see antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell
Cellular bags of...
✓ Soluble factors that contribute to the regulation of innate or adaptive
resistance by affecting other neighboring cells. Can be pro-
inflammatory or anti-inflammatory. Can react quickly or be more
delayed.
Leukotrines
✓ Released when mast cells degranulate, prolong the inflammatory
process. Cause vasodilation, attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
Prostaglandins
✓ Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site
of injury, pain, and fever.
Chemotactic factors
✓ Biochemical substance that attracts leukocyte to the site of
inflammation
Neutrophils
✓ Predominant leukocyte at work during the early stages of acute
inflammation
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