COMPLETE TEST BANK FOR
Lehne's Pharmacology for Nursing Care, 12th Edition By Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP, RN, ACNP-BC, FAANP|| NEWEST EDITION WITH
ACCURATE ANWERS TO ALL VERIFIED CHAPTERS (01 -113) . Grade A+ TEST BANK
12TH EDITION
,Table of Contents
UNIT I: INTRODUCTION ................................................................................................................................. 7
Chapter 01: Orientation To Pharmacology ............................................................................................... 7
Chapter 02: Application Of Pharmacology In Nursing Practice ................................................................ 9
Chapter 03: Drug Regulation, Development, Names, And Information ................................................. 16
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY ........................................................................................ 19
Chapter 04: Pharmacokinetics ................................................................................................................ 19
Chapter 05: Pharmacodynamics ............................................................................................................. 25
Chapter 06: Drug Interactions ................................................................................................................ 29
Chapter 07: Adverse Drug Reactions And Medication Errors ................................................................. 35
Chapter 08: Individual Variation To Drug Responses ............................................................................. 42
Chapter 09: Genetic And Genomic Considerations ................................................................................ 47
Chapter 10: Introduction To Immunomodulators .................................................................................. 51
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ....................................................................................... 55
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding......................................................... 55
Chapter 12: Drug Therapy In Pediatric Patients ..................................................................................... 60
Chapter 13: Drug Therapy In Older Adults.............................................................................................. 65
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS ....................................................................................... 72
SECTION 1: Introduction ..................................................................................................................... 72
Chapter 14: Basic Principles Of Neuropharmacology ............................................................................. 72
Chapter 15: Physiology Of The Peripheral Nervous System ................................................................... 75
SECTION 2: Cholinergic Drugs ............................................................................................................. 79
Chapter 16: Muscarinic Agonists ............................................................................................................ 79
Chapter 17: Muscarinic Antagonists ....................................................................................................... 83
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis .......................................... 87
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ......................................................... 91
SECTION 3: Adrenergic Drugs.............................................................................................................. 96
Chapter 20: Adrenergic Agonists ............................................................................................................ 96
Chapter 21: Adrenergic Antagonists ..................................................................................................... 102
Chapter 22: Indirect-Acting Antiadrenergic Agents .............................................................................. 109
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ........................................................................................... 114
SECTION 4: Introduction ................................................................................................................... 114
Chapter 23: Introduction To Central Nervous System Pharmacology .................................................. 114
, SECTION 5: Drugs For Neurodegenerative Disorders ....................................................................... 118
Chapter 24: Drugs For Parkinson Disease ............................................................................................. 118
Chapter 25: Drugs For Alzheimer Disease............................................................................................. 125
Chapter 26: Drugs For Multiple Sclerosis.............................................................................................. 130
SECTION 6: Neurologic Drugs............................................................................................................ 136
Chapter 27: Drugs For Seizure Disorders .............................................................................................. 136
Chapter 28: Drugs For Muscle Spasm And Spasticity ........................................................................... 145
SECTION 7: Drugs For Pain ................................................................................................................ 149
Chapter 29: Local Anesthetics............................................................................................................... 150
Chapter 30: General Anesthetics .......................................................................................................... 155
Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Acting Analgesics ....... 162
Chapter 32: Pain Management In Patients With Cancer ...................................................................... 168
Chapter 33: Drugs For Headache .......................................................................................................... 177
SECTION 8: Psychotherapeutic Drugs ............................................................................................... 183
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ..................................................... 183
Chapter 35: Antidepressants ................................................................................................................ 190
Chapter 36: Drugs For Bipolar Disorder ................................................................................................ 199
Chapter 37: Sedative-Hypnotic Drugs ................................................................................................... 204
Chapter 38: Management Of Anxiety Disorders ................................................................................... 212
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder ........ 217
SECTION 9: Substance Use Disorders ............................................................................................... 222
Chapter 40: Substance Use Disorders I: Basic Considerations ............................................................. 222
Chapter 41: Substance Use Disorders II: Alcohol.................................................................................. 227
Chapter 42: Substance Use Disorders III: Nicotine ............................................................................... 235
Chapter 43: Substance Use Disorders IV: Major Drugs Of Abuse Other Than Alcohol And Nicotine... 240
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE ......................................................... 248
Chapter 44: Diuretics ............................................................................................................................ 248
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ........................................ 253
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD ............................................. 259
Chapter 46: Review Of Hemodynamics ................................................................................................ 259
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System ......................................... 262
Chapter 48: Calcium Channel Blockers ................................................................................................. 268
Chapter 49: Vasodilators....................................................................................................................... 271
, Chapter 50: Drugs For Hypertension .................................................................................................... 276
Chapter 51: Drugs For Heart Failure ..................................................................................................... 285
Chapter 52: Antidysrhythmic Drugs ...................................................................................................... 294
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels ...................................... 304
Chapter 54: Drugs For Angina Pectoris ................................................................................................. 312
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ...................................................... 320
Chapter 56: Management Of ST-Elevation Myocardial Infarction ....................................................... 328
Chapter 57: Drugs For Hemophilia ....................................................................................................... 333
Chapter 58: Drugs For Deficiency Anemias........................................................................................... 339
Chapter 59: Hematopoietic Agents....................................................................................................... 346
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ....................................................................................... 351
Chapter 60: Drugs For Diabetes Mellitus .............................................................................................. 351
Chapter 61: Drugs For Thyroid Disorders ............................................................................................. 359
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function................................................... 365
Chapter 63: Drugs For Disorders Of The Adrenal Cortex ...................................................................... 371
UNIT IX: REPRODUCTIVE HEALTH ............................................................................................................. 376
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive Applications ..... 376
Chapter 65: Birth Control ...................................................................................................................... 381
Chapter 66: Drug Therapy For Infertility ............................................................................................... 388
Chapter 67: Drugs That Affect Uterine Function .................................................................................. 394
Chapter 68: Androgens ......................................................................................................................... 399
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ................................... 405
Chapter 70: Review Of The Immune System ........................................................................................ 410
UNIT X: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ........................................ 415
Chapter 71: Childhood Immunization ................................................................................................... 415
Chapter 72: Immunosuppressants ........................................................................................................ 422
Chapter 73: Antihistamines .................................................................................................................. 427
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-Inflammatory Drugs And Acetaminophen
.............................................................................................................................................................. 433
Chapter 75: Glucocorticoids In Nonendocrine Disorders ..................................................................... 440
Chapter 76: Drug Therapy For Rheumatoid Arthritis............................................................................ 447
UNIT XI: DRUGS FOR BONE AND JOINT DISORDERS ................................................................................. 451
Chapter 77: Drug Therapy For Gout...................................................................................................... 451
, Chapter 78: Drugs Affecting Calcium Levels And Bone Mineralization ................................................ 455
Chapter 79: Drugs For Asthma And Chronic Obstructive Pulmonary Disease...................................... 463
UNIT XII: RESPIRATORY TRACT DRUGS ..................................................................................................... 473
Chapter 80: Drugs For Allergic Rhinitis, Cough, And Colds ................................................................... 473
Chapter 81: Drugs For Peptic Ulcer Disease ......................................................................................... 479
UNIT XIII: GASTROINTESTINAL DRUGS ...................................................................................................... 486
Chapter 82: Laxatives ............................................................................................................................ 486
Chapter 83: Other Gastrointestinal Drugs ............................................................................................ 493
Chapter 84: Vitamins ............................................................................................................................ 502
UNIT XIV: NUTRITION AND COMPLIMENTARY THERAPY .......................................................................... 509
Chapter 85: Drugs For Weight Loss....................................................................................................... 509
Chapter 86: Complementary And Alternative Therapy ........................................................................ 516
Chapter 87: Basic Principles Of Antimicrobial Therapy ........................................................................ 520
UNIT XV: THERAPY OF INFECTIOUS DISEASES........................................................................................... 526
Chapter 88: Drugs That Weaken The Bacterial Cell Wall I: Penicillins .................................................. 526
Chapter 89: Drugs That Weaken The Bacterial Cell Wall II: Other Drugs ............................................. 534
Chapter 90: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others ... 539
Chapter 91: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis......................................... 549
Chapter 92: Sulfonamides And Trimethoprim ...................................................................................... 557
Chapter 93: Drug Therapy For Urinary Tract Infections ....................................................................... 562
Chapter 94: Antimycobacterial Agents ................................................................................................. 570
Chapter 95: Miscellaneous Antibacterial Drugs.................................................................................... 579
Chapter 96: Antifungal Agents .............................................................................................................. 585
Chapter 97: Antiviral Agents I: Drugs For Non-HIV Viral Infections ...................................................... 594
Chapter 98: Antiviral Agents II: Drugs For HIV Infection And Related Opportunistic Infections .......... 601
Chapter 99: Drug Therapy For Sexually Transmitted Diseases ............................................................. 607
Chapter 100: Antiseptics And Disinfectants ......................................................................................... 612
Chapter 101: Anthelmintics .................................................................................................................. 617
UNIT XVI: CHEMOTHERAPY OF PARASITIC DISEASES................................................................................ 621
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents .................................................................... 621
Chapter 103: Antiprotozoal Drugs II: Miscellaneous Agents ................................................................ 627
Chapter 104: Ectoparasiticides ............................................................................................................. 629
Chapter 105: Basic Principles Of Cancer Chemotherapy ...................................................................... 635
,UNIT XVII: CANCER CHEMOTHERAPY........................................................................................................ 642
Chapter 106: Anticancer Drugs I: Cytotoxic Agents .............................................................................. 642
Chapter 107: Anticancer Drugs II: Noncytotoxic Agents....................................................................... 650
Chapter 108: Drugs For The Eye ........................................................................................................... 655
UNIT XVIII: MISCELLANEOUS DRUGS AND THERAPIES ............................................................................. 661
Chapter 109: Drugs For The Skin .......................................................................................................... 661
Chapter 110: Drugs For The Ear ............................................................................................................ 670
Chapter 111: Management Of Poisoning ............................................................................................. 676
UNIT XIX: TOXICOLOGY ............................................................................................................................. 682
Chapter 112: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ............................ 682
Chapter 113: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism.............................. 687
,UNIT I: INTRODUCTION
Chapter 01: Orientation To Pharmacology
Burchum: Lehne’s Pharmacology For Nursing Care, 12th Edition
MULTIPLE CHOICE
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do This, The
Nurse Will Rely On Knowledge Of Which Topic?
A. Clinical Pharmacology
B. Drug Efficacy
C. Pharmacokinetics
D. Pharmacotherapeutics
ACCURATE ANS>> D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent Conditions.
Clinical Pharmacology Is Concerned With All Aspects Of Drug-Human Interactions. Drug Efficacy
Measures The Extent To Which A Given Drug Causes An Intended Effect. Pharmacokinetics Is The Study
Of The Impact Of The Body On A Drug.
PTS: 1
2. What Is A Desired Outcome When A Drug Is Described As Easy To Administer?
A. It Can Be Stored Indefinitely Without Need For Refrigeration.
B. It Does Not Interact Significantly With Other Medications.
C. It Enhances Patient Adherence To The Drug Regimen.
D. It Is Usually Relatively Inexpensive To Produce.
ACCURATE ANS>> C
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are More Likely To
Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The Other Attributes Listed, But
Those Properties Are Independent Of Ease Of Administration.
PTS: 1
3. A Patient Tells The Nurse That An Analgesic He Will Begin Taking May Cause Drowsiness And
Will Decrease Pain Up To 4 Hours At A Time. Based On This Understanding Of The Drug’s Effects By The
Patient, The Nurse Will Anticipate Which Outcome?
A. Decreased Chance Of Having A Placebo Effect
, B. Decreased Motivation To Take The Drug
C. Improved Compliance With The Drug Regimen
D. Increased Likelihood Of Drug Overdose
ACCURATE ANS>> C
A Drug Is Effective If It Produces The Intended Effects, Even If It Also Produces Side Effects. Patients Who
Understand Both The Risks And Benefits Of Taking A Medication Are More Likely To Comply With The
Drug Regimen.
PTS: 1
MULTIPLE RESPONSE
1. What Are Considered The ‘Big Three’ Properties Of An Ideal Drug? (Select All That Apply.)
A. Irreversible Action
B. Effectiveness
C. Safety
D. Selectivity
E. A Recognizable Trade Name
ACCURATE ANS>> B, C, D
The ‘Big Three’ Properties Of The Ideal Drug Are Effectiveness, Safety, And Selectivity. PTS: 1
2. Before Administering A Medication, What Does The Nurse Need To Know To Evaluate How
Individual Patient Variability Might Affect The Patient’s Response To The Medication? (Select All That
Apply.)
A. Chemical Stability Of The Medication
B. Ease Of Administration
C. Family Medical History
D. Patient’s Age
E. Patient’s Diagnosis
ACCURATE ANS>> C, D, E
