Biochemistry ACS: – Questions And Answers (100%)
Nonpolar, aliphatic AA's Right Ans - gly, ala, pro, val, leu, ile, met
Aromatic AA's Right Ans - phe, Tyr, trp
What wavelength do aromatic aa's absorb light? Right Ans - 280 nm
Polar, uncharged aa's Right Ans - Ser, Thr, Cys, Asp, Glu
Are Disulfide bonds hydrophobic or hydrophilic? Right Ans - hydrophobic
Polar, Positively charged (basic) aa's Right Ans - Lys, Arg, His
Polar, negatively charged (acidic) aa's Right Ans - Asp, Glu
What is the pI formula? Right Ans - (pK1 + pK2)/2
When pH is below pI what is the net charge? Right Ans - positive
For a hydropathy index, what does it show and what does a large, positive
index indicate? Right Ans - hydrophobicity, very hydrophobic
Naming of a polypeptide begins at which end? Right Ans - the amino end
How much does an amino acid weigh in a peptide? by itself? What accounts
for the difference? Right Ans - 110 Daltons and 128 Daltons. 18 Da of water
A protein with all the same subunits Right Ans - homomeric
a protein with 2 or more difference subunits Right Ans - heteromeric
Non-amino acid components of a protein, tightly or covalently bound Right
Ans - prosthetic groups
Non-amino acid components of a protein, loosely bound Right Ans -
coenzymes
,general name for Non-amino acid components of a protein Right Ans -
cofactors
How many molecules of ATP per molecule of glucose (after glycolysis)?
Right Ans - 2
Glycolysis turns glucose into _____? How many? Right Ans - pyruvate, 2
In anaerobic conditions, pyruvate undergoes which two kinds of _______?
Right Ans - ethanol or lactic acid fermentation
In aerobic conditions, 2 pyruvate is turned into ______? How many? By
product? Right Ans - acetyl-CoA, 2, 2CO2
Acetyl-CoA enters the ________ and produces ____ and ____ Right Ans - citric
acid cycle, 4CO2, 4H2O
Ethanol fermentation produces ____ and ____ Right Ans - 2 ethanol and 2
CO2
Lactic Acid Fermentation produces Right Ans - 2 Lactate
During stage 1 of glycolysis, one glucose molecule is converted into 2 ____ by
consuming 2 ____ Right Ans - GAP molecules, ATP
During stage 2 of glycolysis, 2 GAP molecules are converted to 2 _____ and
produce a total of 4 ______ and 2 ______ Right Ans - pyruvate, ATP, NADH
Spatial arrangement of atoms in a protein in a cell in its functional form.
Stability of a protein refers to the ability to keep this form. Right Ans -
Native Conformation
What are the three weak interactions that hold proteins in their stable
conformations? Right Ans - hydrophobic interactions, hydrogen bonding,
ionic bonding
What is a strong interaction that stabilizes protein conformation? Right
Ans - disulfide bonds
, What is the name of the bond angle associated with the bond between the
alpha carbon and amide nitrogen? Right Ans - Phi
What is the name of the bond angle associated with the bond between the
alpha carbon and carbonyl carbon? Right Ans - Psi
This structure occurs when each dihedral angel phi and psi remain nearly the
same throughout the segment. Right Ans - Secondary Structure
T/F alpha helices and beta sheets are stabilized by hydrogen bonds between
H, O, or N's only on the aa backbone. Right Ans - True
What is a difference of the stabilizing H-bonding between alpha helices and
beta sheets? Right Ans - location of residues
In an alpha helix, how many aa residues away is the amide H atom from the
carbonyl O? Right Ans - 4
How are R groups situated in alpha helices? Right Ans - projecting away
from helix
What are two amino acids that can act as alpha helix breakers? Right Ans -
proline and glycine
How are adjacent strands within a beta sheet stabilized? Right Ans -
hydrogen bonds between carbonyl O and amide H
If 2 beta sheets are stacked on each other, what can be said about the R groups
of the aa's? Right Ans - they are small
type of beta sheet where adjacent chains run in the same amino-to carboxyl
direction Right Ans - parallel
type of beta sheet where adjacent chains run in the opposite amino to
carboxyl direction Right Ans - antiparallel
Which type of beta sheet is most stable? Right Ans - antiparallel