A
VI
TU
IS
M
NURS 5334 - M1
O
PHARMACOLOGY Verified 2024
A
Questions and Answers 100%
N
Correct Guaranteed PASS
JP
Prescriptive Authority - ANSWER legal route to prescribe independently and without
limitation
Parts of a prescription - ANSWER - prescriber name
- license number
- contact information
, - DEA number (prescriber and supervising)
- patient name
- DOB
- allergies
- name of medication
- indication
- strength
- frequency
- signature
A
SIG - ANSWER "let it be labeled"; instructions for the prescription
VI
Pharmacokinetics - ANSWER the study of the drug movement throughout the body
TU
Ways for drugs to cross the cell membrane - ANSWER 1. Channels
2. Pore transport systems - P-glycoprotein system
3. Direct penetration
Absorption - ANSWER the drug's movement from the site of administration into the
IS
blood
Factors that affect absorption: - ANSWER rate of dissolution, surface area, blood
M
flow, lipid solubility, pH partitioning
O
pH partitioning or ion trapping - ANSWER drug molecules tend to accumulate on the
side of the membrane where pH most favors ionization - i.e. Acidic drugs accumulate on
the alkaline side, and basic drugs accumulate on the acidic side
A
Distribution - ANSWER the drug's movement from the blood into the interstitial
N
space of tissues and from there into the cells
JP
Factors that affect distribution: - ANSWER circulation, membrane permeability,
protein binding
Metabolism (biotransformation) - ANSWER enzymatically mediated alteration of
drug structure
Substrate - ANSWER drugs that are metabolized by the P450 hepatic enzymes
Inducer - ANSWER increase the rate of metabolism
VI
TU
IS
M
NURS 5334 - M1
O
PHARMACOLOGY Verified 2024
A
Questions and Answers 100%
N
Correct Guaranteed PASS
JP
Prescriptive Authority - ANSWER legal route to prescribe independently and without
limitation
Parts of a prescription - ANSWER - prescriber name
- license number
- contact information
, - DEA number (prescriber and supervising)
- patient name
- DOB
- allergies
- name of medication
- indication
- strength
- frequency
- signature
A
SIG - ANSWER "let it be labeled"; instructions for the prescription
VI
Pharmacokinetics - ANSWER the study of the drug movement throughout the body
TU
Ways for drugs to cross the cell membrane - ANSWER 1. Channels
2. Pore transport systems - P-glycoprotein system
3. Direct penetration
Absorption - ANSWER the drug's movement from the site of administration into the
IS
blood
Factors that affect absorption: - ANSWER rate of dissolution, surface area, blood
M
flow, lipid solubility, pH partitioning
O
pH partitioning or ion trapping - ANSWER drug molecules tend to accumulate on the
side of the membrane where pH most favors ionization - i.e. Acidic drugs accumulate on
the alkaline side, and basic drugs accumulate on the acidic side
A
Distribution - ANSWER the drug's movement from the blood into the interstitial
N
space of tissues and from there into the cells
JP
Factors that affect distribution: - ANSWER circulation, membrane permeability,
protein binding
Metabolism (biotransformation) - ANSWER enzymatically mediated alteration of
drug structure
Substrate - ANSWER drugs that are metabolized by the P450 hepatic enzymes
Inducer - ANSWER increase the rate of metabolism
