Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a patient who is having
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a computed tomography (CT) scan. The nurse working on the oncology unit a
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dministers chemotherapy to patients who have cancer. At the Public Health De
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partment, a nurse administers a measles-mumps-
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rubella (MMR) vaccine toa 14-month-
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old child as a routine immunization. Which branch of pharmacology best desc
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ribes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are inv
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olved with clinical pharmacology or pharmacotherapeutics, which is a branch
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of pharmacology that deals with the uses of drugs to treat, prevent, and diagno
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se disease. The radiology nurse is administering a drug to help diagnose a dise
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ase. The oncology nurse is administering a drug to help treat adisease. Pharma
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coeconomics includes any costs involved in drug therapy. (i (i (i (i (i (i (i
Pharmacodynamics involves how a drug affects the body and (i (i (i (i (i (i (i (i i(
pharmacokinetics is how the body acts on the body. (i (i (i (i (i (i (i (i
2.
A physician has ordered intramuscular (IM) injections of morphine, a narco
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tic, every 4 hours as needed for pain in a motor vehicle accident victim.The n
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urse is aware this drug has a high abuse potential. Under what categorywould
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morphine be classified? (i (i
A) Schedule I (i
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B) Schedule II
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C) Schedule III (i
D) Schedule IV (i
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs beca
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use of severe dependence liability. Schedule I drugs have high abuse potentia
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l and no accepted medical use. Schedule III drugs have a lesser abuse potenti
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al than II and an accepted medical use. Schedule IV drugs havelow abuse pot
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ential and limited dependence liability.
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3.
When involved in phase III drug evaluation studies, what responsibilitie
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swould the nurse have?
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A) Working with animals who are given experimental drugs (i (i (i (i (i (i (i
B) Choosing appropriate patients to be involved in the drug study (i (i (i (i (i (i (i (i ( i
C) Monitoring and observing patients closely for adverse effects (i (i (i (i (i (i (i
D) Conducting research to determine effectiveness of the drug (i (i (i (i (i (i (i
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in whichp
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atients are asked to record any symptoms they experience while taking thedr
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ugs. Nurses may be responsible for helping collect and analyze the informati
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on to be shared with the Food and Drug Administration (FDA) butwould not
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conduct research independently because nurses do not prescribe medications
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. Use of animals in drug testing is done in the preclinical trials. Select patient
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s who are involved in phase II studies to participate in studies where the parti
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cipants have the disease the drug is intended to treat. These patients are moni
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tored closely for drug action and adverse effects. Phase I studies involve heal
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thy human volunteers who are usually paid for their participation. Nurses ma
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y observe for adverse effects and toxicity.
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4.
What concept is considered when generic drugs are substituted for bra
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ndname drugs? i( (i
A) Bioavailability
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