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Summary similarities and differences between antibiotics

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ways to group antibiotics to easily remember antibiotics similarities and differences

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  • November 29, 2024
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  • 2023/2024
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bacteristatic by inhibiting
protien synthesis
BROAD SDEL . ANTIBIOTICS
carbapenams(Imipen)
Aminoglycosides (gentamycin) & 305 tryciclic glycoprotiens (Vancomycin) -
G( ) +




tetracycline (doxycycline) tetracycline (doxycycline)
mainly for G(t)
macrolides (erythromycin) 50s ampicillan
For SOME DC+
cell wall gramc-
bactericidal by inhibiting aminoglycosides
-
severe Staphylo-
Synthesis-betalactams coccus infections Gt
mefoxin rocephine , maxi as Sulfanomides
phalosporinsChexamef
,



bindoOglyca -
,




WiRNAsyn imacrolides most effective
truccigycoprotienvancomycin)
(interferes
against gramt)
cephalosporin
mainly for 6Ct
VANCOMY(IN also is bactericidal by inhibiting affect Plasma mem mainly for 6( + ) -pamoxicilian
cell wall synthesis , but in a different way and interfere WI
vancomycin
RNA Synthesis
Antimetabolites mainly for 67)-Acephalosporin ,


aminoglycosides ,


sulfonamides - prevent bacterial Synthesis of folic acid macrolides
quinolones

DNA replication GRAM (+ ) ANTIBIOTICS

quinolones Penicill in
-




drug similarities

aminoglycosides & tricyclic glycoprotions
(gentamy(in) (vancomycin)
-
both have very small theraputic windows
-
both cause ototoxicity
important to monitor
-
both cause nephrotoxicity - it is
serum creatinine levels
they are different in that
cause tinnitus (Gentamycin (
aminoglycosides also can
aminoglycosides
have similar MoA as
aminoglycosides bind to ribosome group 30 a

fetralycline (doxycycline)
to inhibit protien synthesis , whereas vancomycin
inhibits cell Wall Synthesis they both bind to 303

Penicillin Cephalosporin ,
carbapenams
,


tricyclic glycoprotiens all are bactericidal by

inhibiting cell wall Synthesis
a
minoglycosides , tricyclic glycopeptides macrolides
are all bacteriostatic by
inhibiting protien synthesis
aminoglycosides Stricyclic glycopeptides bind to 30
macrolides bind to 50s

drug adverse effects that include nu , and
photosensitivity
are : tetracyclines , and sulfamonides

aminoglycosides are typically taken w/ a betalactam

both tetracycline and furoquinolones treat chlamydia

that have cross sensitivity include cephalosporin
drugs
Stricyclic glycoprotiens
aminoglycosides
have small theraputic windows
aminoglycosidess protiens
glyco

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