COMPLETE TEST BANK FOR
Lehne's Pharmacology for Nursing Care 12th Edition
by Jacqueline Rosenjack Burchum DNSc FNP-BC CNE Laura D. Rosenthal DNP RN
ACNP-BC FAANP ||NEWEST EDITION WITH ALL VERIFIED CHAPTERS.(2024 – 2025 BY
Jacqueline Rosenjack )
12TH EDITION
,Table of Contents
UNIT I: INTRODUCTION ....................................................................................................................................... 6
Chapter 1: Orientation To Pharmacology .............................................................................................................. 6
Chapter 2: Application Of Pharmacology In Nursing Practice .............................................................................. 8
Chapter 3: Drug Regulation, Development, Names, And Information ................................................................ 13
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY ...................................................................................... 16
Chapter 4: Pharmacokinetics ................................................................................................................................ 16
Chapter 5: Pharmacodynamics ............................................................................................................................ 21
Chapter 6: Drug Interactions ................................................................................................................................ 24
Chapter 7: Adverse Drug Reactions And Medication Errors ............................................................................... 29
Chapter 8: Individual Variation In Drug Responses ............................................................................................ 35
Chapter 9: Drug Therapy During Pregnancy And Breast-Feeding ...................................................................... 39
Chapter 10: Drug Therapy In Pediatric Patients................................................................................................... 43
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN .................................................................................... 47
Chapter 11: Drug Therapy In Geriatric Patients................................................................................................... 47
Chapter 12: Basic Principles Of Neuropharmacology ......................................................................................... 52
Chapter 13: Physiology Of The Peripheral Nervous System ............................................................................... 56
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS ..................................................................................... 61
Chapter 14: Muscarinic Agonists And Antagonists ............................................................................................. 61
Chapter 15: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis ...................................................... 65
Chapter 16: Drugs That Block Nicotinic Cholinergic Transmission: NeuromuscularBlocking Agents And
Ganglionic Blocking Agents ................................................................................................................................ 69
Chapter 17: Adrenergic Agonists ......................................................................................................................... 74
Chapter 18: Adrenergic Antagonists .................................................................................................................... 81
Chapter 19: Indirect-Acting Antiadrenergic Agents ............................................................................................ 88
Chapter 20: Introduction To Central Nervous System Pharmacology ................................................................. 93
Chapter 21: Drugs For Parkinson’s Disease ......................................................................................................... 96
Chapter 22: Alzheimer’s Disease ....................................................................................................................... 104
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS .......................................................................................... 108
Chapter 23: Drugs For Multiple Sclerosis .......................................................................................................... 108
Chapter 24: Drugs For Epilepsy ......................................................................................................................... 115
Chapter 25: Drugs For Muscle Spasm And Spasticity ....................................................................................... 123
Chapter 26: Local Anesthetics ............................................................................................................................ 127
Chapter 27: General Anesthetics ........................................................................................................................ 132
Chapter 28: Opioid (Narcotic) Analgesics, Opioid Antagonists, And NonopioidCentrally Acting Analgesics 138
Chapter 29: Pain Management In Patients With Cancer .................................................................................... 145
Chapter 30: Drugs For Headache ....................................................................................................................... 152
Chapter 31: Antipsychotic Agents And Their Use In Schizophrenia ................................................................. 157
Chapter 32: Antidepressants ............................................................................................................................... 166
Chapter 33: Drugs For Bipolar Disorder ............................................................................................................ 174
Chapter 34: Sedative-Hypnotic Drugs................................................................................................................ 179
Chapter 35: Management Of Anxiety Disorders ................................................................................................ 188
, Chapter 36: Central Nervous System Stimulants And Attention-Deficit/HyperactivityDisorder...................... 192
Chapter 37: Drug Abuse I: Basic Considerations ............................................................................................... 198
Chapter 38: Drug Abuse II: Alcohol .................................................................................................................. 201
Chapter 39: Drug Abuse III: Nicotine And Smoking ......................................................................................... 209
Chapter 40: Drug Abuse IV: Major Drugs Of Abuse Other Than Alcohol And Nicotine ................................. 214
Chapter 41: Diuretics .......................................................................................................................................... 224
Chapter 42: Agents Affecting The Volume And Ion Content Of Body Fluids .................................................. 229
Chapter 43: Review Of Hemodynamics ............................................................................................................. 235
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE .............................................. 238
Chapter 44: Drugs Acting On The Renin-Angiotensin-Aldosterone System..................................................... 238
Chapter 45: Calcium Channel Blockers ............................................................................................................. 243
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD .................................. 246
Chapter 46: Vasodilators .................................................................................................................................... 246
Chapter 47: Drugs For Hypertension ................................................................................................................. 251
Chapter 48: Drugs For Heart Failure.................................................................................................................. 261
Chapter 49: Antidysrhythmic Drugs................................................................................................................... 270
Chapter 50: Prophylaxis Of Coronary Heart Disease: Drugs That Help NormalizeCholesterol And Triglyceride
Levels ................................................................................................................................................................. 279
Chapter 51: Drugs For Angina Pectoris ............................................................................................................. 287
Chapter 52: Anticoagulant, Antiplatelet, And Thrombolytic Drugs .................................................................. 295
Chapter 53: Management Of ST-Elevation Myocardial Infarction .................................................................... 303
Chapter 54: Drugs For Hemophilia .................................................................................................................... 308
Chapter 55: Drugs For Deficiency Anemias ...................................................................................................... 313
Chapter 56: Hematopoietic Agents..................................................................................................................... 321
Chapter 57: Drugs For Diabetes Mellitus........................................................................................................... 326
Chapter 58: Drugs For Thyroid Disorders.......................................................................................................... 332
Chapter 59: Drugs Related To Hypothalamic And Pituitary Function............................................................... 339
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ...................................................................................... 345
Chapter 60: Drugs For Disorders Of The Adrenal Cortex ................................................................................. 345
Chapter 61: Estrogens And Progestins: Basic Pharmacology And NoncontraceptiveApplications................... 351
Chapter 62: Birth Control ................................................................................................................................... 356
Chapter 63: Drug Therapy Of Infertility ............................................................................................................ 364
UNIT IX: REPRODUCTIVE HEALTH ............................................................................................................... 371
Chapter 64: Drugs That Affect Uterine Function ............................................................................................... 371
Chapter 65: Androgens ....................................................................................................................................... 376
Chapter 66: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia .............................................. 381
Chapter 67: Review Of The Immune System .................................................................................................... 386
Chapter 68: Childhood Immunization ................................................................................................................ 391
Chapter 69: Immunosuppressants....................................................................................................................... 398
Chapter 70: Antihistamines ................................................................................................................................ 406
UNIT X: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS .............................. 413
Chapter 71: Cyclooxygenase Inhibitors: Nonsteroidal Anti-Inflammatory Drugs AndAcetaminophen ........... 413
, Chapter 72: Glucocorticoids In Nonendocrine Disorders .................................................................................. 422
Chapter 73: Drug Therapy Of Rheumatoid Arthritis.......................................................................................... 429
Chapter 74: Drug Therapy Of Gout ................................................................................................................... 433
Chapter 75: Drugs Affecting Calcium Levels And Bone Mineralization .......................................................... 437
Chapter 76: Drugs For Asthma........................................................................................................................... 446
UNIT XI: DRUGS FOR BONE AND JOINT DISORDERS ................................................................................ 456
Chapter 77: Drugs For Allergic Rhinitis, Cough, And Colds............................................................................. 456
Chapter 78: Drugs For Peptic Ulcer Disease ...................................................................................................... 463
Chapter 79: Laxatives ........................................................................................................................................ 471
UNIT XII: RESPIRATORY TRACT DRUGS ..................................................................................................... 478
Chapter 80: Other Gastrointestinal Drugs .......................................................................................................... 478
Chapter 81: Vitamins .......................................................................................................................................... 489
UNIT XIII: GASTROINTESTINAL DRUGS ...................................................................................................... 495
Chapter 82: Drugs For Weight Loss................................................................................................................... 495
Chapter 83: Basic Principles Of Antimicrobial Therapy ................................................................................... 501
Chapter 84: Drugs That Weaken The Bacterial Cell Wall I: Penicillins ............................................................ 508
UNIT XIV: NUTRITION AND COMPLIMENTARY THERAPY ..................................................................... 514
Chapter 85: Drugs That Weaken The Bacterial Cell Wall II: Cephalosporins, Carbapenems, Vancomycin,
Telavancin, Aztreonam, Teicoplanin, And Fosfomycin .................................................................................... 514
Chapter 86: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides,And Others ................. 519
Chapter 87: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis .................................................... 529
UNIT XV: THERAPY OF INFECTIOUS DISEASES ......................................................................................... 538
Chapter 88: Sulfonamides And Trimethoprim ................................................................................................... 538
Chapter 89: Drug Therapy Of Urinary Tract Infections ..................................................................................... 545
Chapter 90: Antimycobacterial Agents: Drugs For Tuberculosis, Leprosy, AndMycobacterium Avium Complex
Infection ............................................................................................................................................................. 552
Chapter 91: Miscellaneous Antibacterial Drugs: Fluoroquinolones, Metronidazole,Daptomycin, Rifampin,
Rifaximin, Bacitracin, And Polymyxins ............................................................................................................ 564
Chapter 92: Antifungal Agents ........................................................................................................................... 569
Chapter 93: Antiviral Agents I: Drugs For Non-HIV Viral Infections .............................................................. 579
Chapter 94: Antiviral Agents II: Drugs For HIV Infection And Related OpportunisticInfections .................... 585
Chapter 95: Drug Therapy Of Sexually Transmitted Diseases .......................................................................... 593
Chapter 96: Antiseptics And Disinfectants ........................................................................................................ 599
Chapter 97: Anthelmintics .................................................................................................................................. 604
Chapter 98: Antiprotozoal Drugs I: Antimalarial Agents .................................................................................. 609
Chapter 99: Antiprotozoal Drugs II: Miscellaneous Agents .............................................................................. 614
Chapter 100: Ectoparasiticides ........................................................................................................................... 619
Chapter 101: Basic Principles Of Cancer Chemotherapy................................................................................... 624
UNIT XVI: CHEMOTHERAPY OF PARASITIC DISEASES ............................................................................ 630
Chapter 102: Anticancer Drugs I: Cytotoxic Agents.......................................................................................... 630
Chapter 103: Anticancer Drugs II: Hormonal Agents, Targeted Drugs, And OtherNoncytotoxic Anticancer
Drugs.................................................................................................................................................................. 638
Chapter 104: Drugs For The Eye ....................................................................................................................... 645
, Chapter 105: Drugs For The Skin ...................................................................................................................... 654
UNIT XVII: CANCER CHEMOTHERAPY ........................................................................................................ 662
Chapter 106: Drugs For The Ear ........................................................................................................................ 662
Chapter 107: Miscellaneous Noteworthy Drugs ................................................................................................ 667
Chapter 108: Dietary Supplements ..................................................................................................................... 671
UNIT XVIII: MISCELLANEOUS DRUGS AND THERAPIES ......................................................................... 675
Chapter 109: Management Of Poisoning ........................................................................................................... 675
Chapter 110: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism ....................................... 679
, UNIT I: INTRODUCTION
Chapter 1: Orientation To Pharmacology
MULTIPLE CHOICE
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do
This, TheNurse Will Rely On Knowledge Of:
a. Clinical Pharmacology.
b. Drug Efficacy.
c. Pharmacokinetics.
d. Pharmacotherapeutics.
ACCURATE ANS>>D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent
Conditions. Clinical Pharmacology Is Concerned With All Aspects Of Drug–Human Interactions.Drug
Efficacy Measures The Extent To Which A Given Drug Causes An Intended Effect.
Pharmacokinetics Is The Study Of The Impact Of The Body On A Drug.
DIF: Cognitive Level: Comprehension REF: Four Basic
TermsTOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic And Parenteral
Therapies
2. What Does It Mean When A Drug Is Described As Easy To Administer?
a. It Can Be Stored Indefinitely Without Need For Refrigeration.
b. It Does Not Interact Significantly With Other Medications.
c. It Enhances Patient Adherence To The Drug Regimen.
d. It Is Usually Relatively Inexpensive To Produce.
ACCURATE ANS>>C
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are More
Likely To Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The Other
Attributes Listed, But Those Properties Are Independent Of Ease Of Administration.
DIF: Cognitive Level: Comprehension
REF: Additional Properties Of An Ideal Drug: Ease Of
AdministrationTOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic And Parenteral
Therapies
3. A Patient Tells The Nurse That He Was Told By The Prescriber That The Analgesic He Is
Taking Is Very Effective. Which Statement By The Patient Demonstrates An
Understanding Of The Drug’sEffectiveness?
a. “I Don’t Have To Worry About Toxicity, Since It Takes A Large Amount Of This
Drug ToCause An Overdose.”
b. “It Has No Side Effects And Doesn’t Interact With Other Drugs.”
c. “I Only Have To Take It Every 12 Hours.”
d. “It Might Make Me Sleepy, And It Lessens Pain For Several Hours At A Time.”
ACCURATE ANS>>D
