Exam (elaborations)
Chapter 07 Adaptive Immunity
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- Galen College Of Nursing
Chapter 07 Adaptive Immunity
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Chapter 07: Adaptive ImmunityMULTIPLE CHOICE
1. Which of the following is responsible for initiating clonal selection?
a. T cells
b. B cells
c. Antigens
d. Lymphocytes
ANS: C
The lymphocytes remain dormant until an antigen initiates clonal selection. T cells do not
initiate clonal selection. B cells are antibodies. Lymphocytes are released into the circulation
as immature cells that react with antigens.
REF: p. 159
2. Which patient will develop active immunity? A patient who:
a. has natural exposure to an antigen or receives an immunization.
b. receives preformed antibodies or T cells from a donor.
c. has T cells that become B cells.
d. receives immunoglobulin.
ANS: A
Active immunity occurs either after natural exposure to an antigen or after immunization, not
with preformed antibodies orNthUeRtrSanIsNfoGrmTaBti.onCoOfMT cells into B cells
or as a result of receiving immunoglobulin.
REF: p. 159
3. An experiment is designed to determine specific cell types involved in cell-mediated immune
response. The experimenter is interested in finding cells that attack cells that have specific
antigens. Which cells should be isolated?
a. Lymphokine-producing cells
b. T-cytotoxic cells
c. Helper T cells
d. Macrophages
ANS: B
Cell-mediated immunity is driven by T-cytotoxic (Tc) cells that attack antigens directly
and destroy cells that bear foreign antigens. Lymphokine-producing cells, helper T cells,
and macrophages do not attack antigens directly and destroy cells that bear foreign
antigens.
REF: p. 159
4. A 6-year-old female is diagnosed with a bacterial infection of the respiratory system.
Which of the following will most likely try to fight the antigen?
a. Antibodies
b. Cytotoxic T cells
, c. Self-antigens
d. Helper T cells
ANS: A
Antibodies are produced by plasma cells that mature from lymphocytes, called B lymphocytes
(B cells), in response to an antigen. Cytotoxic T cells do not respond to antigens. Self-antigens
do not respond to antigens. Helper T cells do not respond to antigens.
REF: p. 164, Figure 7-7
5. Which statement indicates a correct understanding of antibodies? The most abundant class
of antibody in the serum is:
a. IgG.
b. IgM.
c. IgA.
d. IgE.
ANS: A
IgG is the most abundant class of immunoglobulins, constituting 80–85% of the
immunoglobulins in the blood.
REF: p. 161
6. The predominant antibody of a typical primary immune response is:
a. IgG.
b. IgM.
c. IgA.
d. IgE.
ANS:
B
IgM is the largest immunoglobulin and is the first antibody produced during the initial, or
primary, response to antigen.
REF: p. 161
7. An immunology nurse is caring for a patient. While planning care, which principle will the
nurse remember? The primary role of IgA1 is to prevent infections in the:
a. blood.
b. kidneys.
c. lungs.
d. mucous membranes.
ANS: A
IgA1 is found predominantly in the blood.
REF: p. 161
8. A 23-year-old pregnant female visits her primary care provider for her final prenatal checkup.
The primary care provider determines that the fetus has developed an infection in utero.
Which of the following would be increased in the fetus at birth?
a. IgG
b. IgA
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