lehninger Principles of Biochemistry- Chapter 11 Exam Questions Answered Correctly Graded A+ (Latest Update 2024)
Micelles - Answers Spherical structures that contain anywhere from a few dozen to a few thousand amphipathic molecules. The non polar portions in the interior and the polar portions at...
Micelles - Answers Spherical structures that contain anywhere from a few dozen to a few thousand
amphipathic molecules. The non polar portions in the interior and the polar portions at the exterior
surface, exposed to water
Fluid Mosaic Model - Answers The concept that cell membranes are lipid bilayer structures that contain
an assortment of polar lipids and proteins in a dynamic fluid arrangement
Bilayer - Answers A second type of lipid aggregate in water, in which 2 lipid monolayers (leaflets) form a
2-dimensional sheet.
Vesicle - Answers Is the result of a 2-dimensional bilayer folding on itselt to form a closed bilayer, a 3-
dimensional hollow vesiccle (liposome) enclosing an aqueous cavity.
Integral membrane proteins - Answers Firmly associated with the lipid bilayer and are removable only by
agents that interfere with hydrophobic interactions, such as detergents, organic solvents, or
denaturants.
Peripheral membrane proteins - Answers Associate with the membrane through electrostatic
interactions and hydrogen bonding with the hydrophilic domains of integral proteins and with the polar
head groups of lipids. They can be released by relatively mild treatments that interfere with electrostatic
interactions or break hydrogen bonds; a commonly used agent is carbonate at high pH.
Amphitropic proteins - Answers Found both in the cytosol and in association with membranes. Generally
the reversible association of amphitrophic proteins with the membrane is regulated; for example
phosphorylation or ligand binding can force a conformational chain the protein, exposing a membrane-
binding site that was previously inaccessible.
Membrane Proteins topology - Answers Localization of protein domains relative to the lipid bilayer.
Glycophorin - Answers Erythrocyte glycoprotein that spans the plasma membrane.
Annular lipids - Answers Lipids that form a bilayer shell (annulus) around the protein, orientated roughly
as expected for phospholipids in a bilayer.
Hydropathy index - Answers A scale that expresses the relative hydrophobic and hydrophilic tendencies
of a chemical group
Positive-inside rulet - Answers The positively charged Lys, His, and Arg residues of membrane proteins
occur more commonly on the cytoplasmic face of membranes
B (beta) barrel - Answers 20 or more transmembrane segments form Beta sheets that line a cylinder.
Porins - Answers Proteins that allow certain polar solutes to cross the outer membrane of gram-negative
bacteria such as E.Coli, have many Beta barrels lining the polar transmembrane passage.
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