immunity present at birth and includes biochemical, physical, and mechanical
barriers of defense, as well as the inflammatory response - innate immunity
(natural immunity)
immunity recieved passively from the mother's antibodies, animal serum, or
antibodies produced in response to disease - acquired immunity
produces active acquired immunity - immunizations
this type of response provides protection against acute, rapidly developing
bacterial and viral infections, immediate - humoral response
this type of response is active against slowly developing bacterial infections and is
involved in autoimmune responses. - cellular response
retrovirus that integrates into the CD4 lymphocytes - HIV
directs immunity and regulates the activity of all immune system cells - CD4+
lymphocytes
compromise of CD4+ lymphocytes leads to what - severe immunodeficiency
,opportunistic infections
malignancies
considered a chronic disorder of impaired immunity - HIV
higher incident rates of HIV occur in what type of groups - minority groups
changes the CD4+ T cell role and its immune system defenses - HIV infection
in early infection before HIV disease is evident, the immune system does what -
attaches and destroys most of the newly created virus particles
what happens to the CD4+ T cell count and viral load during an untreated HIV
infection - CD4+ cell decreases
viral load increases
what usually kills HIV/AIDS patients - opportunistic infections
what s/s do you feel in stage 1 (acute infection phase) of HIV - flu like s/s
how long does it take flu like s/s take to show after contracting the virus - 2-4
weeks
,chronic HIV infection after acute infection stage, can lasts for decades, diagnosis
and meds start here - clinical latency stage (stage 2)
AIDS occurs when CD4 cell count falls below what - 200 cells/mm3
what happens to the CD4 cell count and viral load if the patient is compliant with
meds - CD4 count increase
viral load decreases
if a patient with HIV has a viral load of 100,000 and a CD4 count of 275, what
needs done - find out if they are compliant with meds
can a woman breastfeed if she has HIV - no
we can detect HIV with a viral load as low as what - 20
how to prevent HIV - avoid unprotected sex
abstinence
be faithful
use condom
SP within healthcare
, the higher this is, the greater risk for sexual and perinatal transmission - blood
level of HIV
who should take PreEP - people with risky sexual behavior
people with HIV+ partner
what drugs are used for PreEP - Truvada PO
Discovy PO
if a patient is taking PreEP medications how often do they need renal function
tests - every 3 months
PreEp medications should be avoided in what patients - those with Hep B
what situations would we need to treat patients for HIV exposure - dirty needle
sticks
sexual assault victims
how long do we have to administer postexposure HIV prophylaxis after exposure -
72 hours
what are the 3 drugs used for postexposure HIV prophylaxis - tenofovir
emtricitabine
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