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NURS 5334 FINAL EXAM|| ACTUAL EXAM ALL
QUESTIONS AND 100% CORRECT ANSWERS
ALREADY GRADED A+|| LATEST AND
COMPLETE VERSION 2024-2025 WITH VERIFIED
SOLUTIONS|| ASSURED PASS!!!
Prescribing basics
Prescribing is regulated by state BON
Proper RX
Providers name and address, Telephone
DEA
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with indication/Route and frequency,
Quantity and signature.
Drug Schedules: Most addictive to least
1: Heroin,LSD, MJ
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2: hydrocodone, cocaine, Methamphetamine, methadone, oxycodone, meperidine,
fentanyl, adderall, ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics
The effects of drug on the body. Receptors are large molecules usually proteins,
that interact and mediate the action of drugs
agonist
produce receptor stimulation and a conformational change every time they bind.
Do not need all available receptors to produce a maximum response
Partial agonist
drugs that have properties in b/w those of full agonist and antagonist. They bind to
receptors but when they occupy the receptor sites, they stimulate only some of the
receptors.
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antagonist
drugs with affinity for a receptor but with no intrinsic activity. Affinity allows the
antagonist to bind to receptors, but lack of intrinsic activity prevents the bound
antagonist from causing receptor activation. The block action of drugs (ex. Narcan)
Bioavailabity
% of administered dosage of the drug that survives the first pass through the liver
and reaches the blood stream
what the body does to the drug
absorption, distribution, metabolism, excretion
Distribution
movement of absorbed drug in bodily fluids throughout the body to target tissue.
Properties affecting: lipid/water solubility, PH affects ionization of drug, protein
binding, size of molecule (smaller molecules are more able to diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid soluble will pass), placental barrier
(many drugs can pass)
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Protein binding
unbound drug is free which is active, crosses membrane. Low plasma proteins
result in more free drug. Competition: when 2 highly bound drugs are given it
increases the level of both drugs
Metabolism
take place in the liver mostly. Chemical change of a drug structure to:
CYP450
enzymes constitutes the most important of the phase I metabolizing enzymes
(account for about 75% of drug metabolism in the liver)
Phase 2: conjugation reaction occur leading to large increases in hydrophilicity of
the substrates rendering them more readily excretable
Substrate
