Exam (elaborations)
CHEM 464 Final Questions answers latest update
- Course
- CHEM 464
- Institution
- California State University - Northridge
CHEM 464 Final Questions answers latest update
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CHEM 464 Finaltopoisomerases - control DNA underwinding
histones, condensins, cohesins - provide scaffolds to organize chromosome
structure
introns - nontranslated, intervening DNA segments that don't code for the amino
acid sequence
exons - Coding segments of eukaryotic DNA
more - higher euk generally have ____ introns than exons
centromere - a DNA sequence that functions during cell division as an attachment
point for proteins that link the chromosome to the mitotic spindle
telomeres - sequences at the ends of eukaryotic chromosomes that help stabilize
the chromosome
TTAGGG - human telomere sequence
, underwound DNA - state where DNA has fewer right hand turns per given length
than B form DNA
supercoiled - most cellular DNAs are___________; intrinsic property of DNA
tertiary structure
underwound - supercoiled DNA is ___________; which facilitates the separation
of strands required for replication & transcription
Linking number (Lk) - the number of times the twisting strand penetrates a
surface
Lk - topoisomerases change
Type I - topoisomerases that act by transiently breaking one of the two DNA
strands, passing the unbroken strand through the break and rejoining the breaks
Type II - topoisomerases that break both DNA strands; change the Lk in
increments of 2
plectonemic - supercoiling that extends RH supercoils, the length of the supercoil
axis is 40% of the DNA length; general structure of DNA in solution
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