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BIO 344 Exam 4 Questions answers latest update

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BIO 344 Exam 4 Questions answers latest update

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  • December 5, 2024
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BIO 344 Exam 4

What are the differences between microtubules, intermediate filaments and actin
filaments? - Microtubules- largest, form highways

Intermediate filaments- strongest, elastic, hard to break

Actin filaments- thinnest, controls cell shape, under membrane



What is each type of filament made of? - Microtubules- tubulin heterodimer (α
and β tubulin)

Intermediate filaments- tetramers coiled around each other to make rope like
filament

Actin filaments- identical actin subunits



What are the functions of each type of filament? - Microtubules- cell highway;
forms transportation routes along which organelles, vesicles, and chromosomes
move

Intermediate filaments- strength; keeps individual cells together, keeps many cells
attached

Actin filaments- cell shape



Where in the cell would you find each type of filament? - Microtubules-
centrosomes

, Intermediate filaments- desmosomes



Actin filaments- underneath the cell membrane



Understand polymerization of actin and microtubules - Actin filaments- actin
subunit binds ATP to become apart of a growing actin filament. Once ATP is
bound to the subunit, it attaches to a filament, then the ATP will be hydrolyzed.



Microtubules- heterodimer binds GTP to become a part of a growing microtubule
filament. Once apart of the filament, GTP will become hydrolyzed.



*Study tip: actin binds atp and microtubules bind gtp*



What is the difference between the plus and the minus end of actin and
microtubules? - Both nucleated at their minus end, grow at their plus end



What are GTP caps? What types of filaments have these caps? - When end units
of microtubules are bound to GTP



GTP cap = microtubule grows

No GTP cap = microtubule shrinks

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