Insulin - ANSWER Beta cells from pancreas
Continual release/basal bursts
,Used for some DM2 and all DM1
Caution: hypoglycemia
Given: IV, SQ, Nasal spray
U-100: 100units/mL sol'n (most common)
U-500: 500units/mL sol'n (fewer injections, higher levels of insulin needed)
lispro (Humalog) - ANSWER rapid-acting
SQ
admin: 15 min prior to eating
onset: 5-15 minutes
peak: 1-2 hours
duration: 3-5 hours
(treats for food intake)
regular insulin (Humulin) - ANSWER regular-acting
IV, IVP, IV infusion or SQ
use: DKA or hyperglycemia
Admin: 30 min before eating
Onset: 30-60 min
Peak 2-3 Hours
, Duration: 6-10 hours
(treats for food intake)
insulin isophane (NPH) - ANSWER intermediate, slower-acting
cloudy appearance
admin: 30-45 min prior to eating
onset: 1-2 hours
peak: 4-8 hours
stays in body: 10-18 hours
patient needs to eat consistently
increased risk of hypoglycemia
(treats for food intake)
insulin glargine or detemir (Lantus, Levemir) - ANSWER long-acting, basal
constant insulin level
no swings
given 1xday, approx every 12 hours
NEVER MIX- GIVE ALONE
admin: bedtime
onset: 1-2 hours
NO PEAK
Duration: 24 hours
(treats glucose produced by liver)
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